With people living longer, often with chronic illnesses and disabilities, it is becoming increasingly important to understand how depression, disability, and physical illnesses are interrelated, the mechanisms underlying these interrelationships, and their implications for diagnosis and treatment. This volume synthesizes a carefully selected portion of the knowledge about physical illness and depression that has emerged during the past twenty years.

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Foreword. Preface; C.R. Snyder. 1. Physical Illness and Depression in Older Adults: An Introduction; D.R. Shaffer. Part I: Risk Factors. 2. Depression and Disability; M.L. Bruce. 3. Vascular Disease and Depression: Models of the Interplay Between Psychopathology and Medical Comorbidity; J.M. Lyness, E.D. Craine. 4. Pain, Functional Disability, and Depressed Affect; G.M. Williamson. 5. The Role of Everyday Events in Depressive Symptoms for Older Adults; A.J. Zautra, et al. 6. Caregiving and Detrimental Mental and Physical Health Outcomes; J. Bookwala, et al. Part II: Conditioning Variables and Outcomes. 7. Depression, Immune Function, and Health in Older Adults; K.L. Applegate, et al. 8. Quality of Life, Depression, and End-of-Life Attitudes and Behaviors; M. Powell Lawton. 9. The Activity Restriction Model of Depressed Affect: Antecedents and Consequences of Restricted Normal Activities; G.M. Williamson, D.R. Shaffer. 10. We Should Measure Change - And Here's How; C.E. Lance, et al. Part III: Diagnosis and Treatment. 11. Depression and Physicall Illness in Older Primary Care Patients: Diagnostic and Treatment Issues; H.C. Schulberg, et al. 12. The Relationship of Major Depressive Disorder to Alzheimer's Disease; M.F. Weiner, et al. 13. Pharmacotherapy of Geriatric Depression: Taking the Long View; C.F. Reynolds, et al. 14. A Hope-Based Group Treatment for Depressed Older Adult Outpatients; E.J. Klausner, et al. 15. Complex Unity and Tolerable Uncertainly: Relationships of Physical Disorder and Depression; B. Gurland, et al. Part IV: Summary. 16. Physical Illness and Depression in Elderly Adults: A Summary with Implications for Future Directions in Research and Treatment; L.S. Miller.