Covers all clinically licensed AEDs, including those licensed only in specific countries or that have limited indications; these are presented in alphabetical order for ease of reference

Three separate sections highlight the way AED interactions occur to assist the reader in quickly and easily locating any potential interactions for specific drug classes

Includes details of the mechanism and magnitude of the interaction to inform the reader to anticipate the clinical significance of the drug interaction and thus allow for appropriate and timely dose adjustment to minimize the consequence of the interaction

Autorentext

Philip N. Patsalos is a Consultant Clinical Pharmacologist, a Professor of Clinical Pharmacology and Head of Pharmacology and Therapeutics at the Institute of Neurology - University College London, at the National Hospital for Neurology and Neurosurgery, Queen Square and at the Epilepsy Society, Chalfont St Peter, UK.

Professor Patsalos' clinical and research interests relate to the therapeutics of epilepsy and include: new drug treatments and strategies, new drug development (Phase II and III trials) and formulations, pharmacokinetic profiling and drug interactions. He has in excess of 200 publications (books, book chapters and peer reviewed papers) and has served on various International League Against Epilepsy committees including the Commission on Therapeutic Strategies, the Sub-Commission on Polytherapy and Drug Interaction and the Sub-Commission on Therapeutic Drug Monitoring.

He is presently an Editorial Board member of numerous journals including Drugs, EpilepsyResearch and Treatment, European Neurology Journal, Expert Opinion on Emerging Drugs, Expert Review of Clinical Pharmacology and Therapeutic Drug Monitoring. He is also Associate Editor of Epilepsia and of the journal Epileptologia.

Klappentext

Antiepileptic Drug Interactions: A Clinical Guide, Second Edition provides a pocket-sized, systematic description of the most clinically relevant drug interactions that occur between AEDs and also between AEDs and non-AEDs. AEDs are presented alphabetically and by drug class in three sections for easy access: Drug interactions between AEDs; Drug interactions between AEDs and non-AEDs: Interactions affecting AEDs; and Drug interactions between AEDs and non-AEDs: Interactions affected by AEDs.

Antiepileptic Drug Interactions: A Clinical Guide, Second Edition should help physicians make more rational choices when polytherapy regimens are indicated and should be of interest to all who treat patients with epilepsy: neurologists and neurosurgeons, trainees at all levels, general practitioners and epilepsy nurse specialists.

Inhalt

Introduction.- Section 1: Drug interactions between AEDs.- Section 2: Drug interactions between AEDs and non-AEDs: Interactions affecting AEDs.- Section 3: Drug interactions between AEDs and non-AEDs: Interactions affected by AEDs.