This book offers a comprehensive overview of structural and functional neuroimaging findings related to the pathophysiology of primary and secondary headaches. In addition, it provides recommendations for best practice and decision-making in ordering neuroimaging investigation when faced with patients suffering from a vast range of headache types, whether in everyday practice, or in an ambulance or emergency room. Hopefully, this book will promote the adequate use of cutting-edge neuroimaging in headache research and in ongoing clinical trials in major neurology centers in Europe and worldwide. The structure of the book is designed to cover the basic principles of neuroimaging that neurologists should be aware of when making decisions about headache management, scientifically based recommendations for the application of different neuroimaging protocols in the emergency department and in the neurological clinic, the latest findings from advanced neuroimaging related to migraine without and with aura, chronic migraine and medication overuse headache, cluster headache, trigeminal neuralgia and other forms of headache and orofacial pain. Finally, the book contains a chapter on future directions in headache neuroimaging and the implementation of machine and deep learning algorithms in the neuroimaging and classification of headaches and the prediction of treatment outcomes. Neurologists, radiologists and physicians involved in pain medicine will benefit from this book, by having access to comprehensive, state-of-the-art knowledge on research and clinical practice in the field of headache neuroimaging. Furthermore, it could be a compendium for medical students and residents who are usually introduced to headache neuroimaging through multidisciplinary university programmes. Headache patients will also benefit from this book, being helped to better understand their condition from a neuroimaging techniques perspective.

Autorentext

Igor Petrušic MD, PhD, (radiologist, pain medicine subspecialist, and clinical neuroscientist) is a senior research associate at the Laboratory for Advanced Analysis of Neuroimages, Faculty of Physical Chemistry, University of Belgrade, Serbia. He has a great interest in developing electrophysiological and neuroimaging protocols in migraine with aura research, primarily focused on discovering biomarkers for different levels of migraine aura complexity. He also aims to incorporate a multidisciplinary approach in headache research to boost advancements in the diagnosis and prediction of treatment outcomes. He published more than 20 original research articles related to the migraine and neuroimaging field. He is a member of the Editorial Board of the Journal of Headache and Pain.

Yonggang Wang MD, PhD, (neurologist, headache specialist) is the director of headache department, Beijing Tiantan Hospital, Capital Medical University and the director of Headache Association of the Chinese Society of Neurology. His research interests are focused on the application of multimodal neuroimaging in the diagnosis and treatment of headache and the study of neural mechanisms. He is also committed to headache education and has trained hundreds of headache professionals and plans to train 5,000 headache specialists. He published more than 50 original research articles. He. also, is a member of the associate editor of the Journal of Headache and Pain.