This book constitutes the refereed proceedings of the 5th International Conference on Networking Systems of AI, INSAI 2025, which took place in Shenzhen, China, during November 15-17, 2025.

The 20 full papers and 2 short papers included in this book were carefully reviewed and selected from 52 submissions. They are organized into the following topical sections: Deep learning and AI method; Communication and Edge Computing; Behavior Modeling and Social Computing; Virtual Reality and Intelligent Application.