Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems presents a significant and up-to-date review of various integrated approaches for bacterial detection. Distinguished engineers and scientists from key institutions worldwide have contributed chapters that provide a deep analysis of their particular subject; at the same time, each topic is framed within the context of this integrated approach. This work is a comprehensive approach to bacterial detection requiring a thorough knowledge of the subject and an effective integration of other disciplines in order to appropriately convey the state-of-the-art fundamentals and applications of the involved disciplines.

The book consists of four parts:

The first part provides an introduction to pathogenic bacteria and sampling techniques and an overview of the rapid microbiological methods.

The second part describes the different transducers used for the detection of bacteria. It covers the theory behind each technique and provides a state-of-the-art review of all the new technologies used for the detection of bacteria in detail. Strategies and future prospects are suggested at the end of each chapter for developing future technologies to achieve a better sensitivity and swifter detection of bacteria.

The third part gives an account of the different recognition receptors used in the various methods for the detection of bacteria. It describes in detail the use of immunoassays, nucleic acids, oligonucleotide microarrays, carbohydrates, aptamers, protein microarrays, bacteriophages, phage displays and molecular imprinted polymers as recognition elements.

The fourth part covers the microsystems used for detection/identification and bacterial manipulation such as bacteria lysis and PCR in microfluidics, dielectrophoresis, ultrasonic manipulation techniques and mass spectrometry techniques.

Students and researchers whoneed a solid foundation or reference and practitioners interested in discovering more about the state-of-the-art methods of bacterial detection will find this book invaluable. This book is directed at academics and undergraduate and postgraduate students who work in areas related to bacterial detection. It may also serve as an important reference for professionals working in different fields, including biomedical science, physical science, microsystems engineering, nanotechnology, veterinary science, food quality assurance, bioterrorism and security as well as health surveillance.

Inhalt
to Pathogenic Bacteria.- Sample Preparation An Essential Prerequisite for High-Quality Bacteria Detection.- Detection of Bacterial Pathogens in Different Matrices: Current Practices and Challenges.- Overview of Rapid Microbiological Methods.- Biosensors.- Surface Plasmon Resonance (SPR) Sensors for the Detection of Bacterial Pathogens.- Bacterial Detection Using Evanescent Wave-Based Fluorescent Biosensors.- Fiber Optic Biosensors for Bacterial Detection.- Integrated Deep-Probe Optical Waveguides for Label Free Bacterial Detection.- Interferometric Biosensors.- Luminescence Techniques for the Detection of Bacterial Pathogens.- Porous and Planar Silicon Sensors.- Acoustic Wave (TSM) Biosensors: Weighing Bacteria.- Amperometric Biosensor for Pathogenic Bacteria Detection.- Microbial Genetic Analysis Based on Field Effect Transistors.- Impedance-Based Biosensors for Pathogen Detection.- Label-Free Microbial Biosensors Using Molecular Nanowire Transducers.- Magnetic Techniques for Rapid Detection of Pathogens.- Cantilever Sensors for Pathogen Detection.- Detection and Viability Assessment of Endospore-Forming Pathogens.- Label-Free Fingerprinting of Pathogens by Raman Spectroscopy Techniques.- Biorecognition.- Antibodies and Immunoassays for Detection of Bacterial Pathogens.- Rapid Nucleic Acid-Based Diagnostics Methods for the Detection of Bacterial Pathogens.- Oligonucleotide and DNA Microarrays: Versatile Tools for Rapid Bacterial Diagnostics.- Pathogenic Bacterial Sensors Based on Carbohydrates as Sensing Elements.- Aptamers and Their Potential as Recognition Elements for the Detection of Bacteria.- Protein Microarray Technologies for Detection and Identification of Bacterial and Protein Analytes.- Bacteriophage: Powerful Tools for the Detection of BacterialPathogens.- Phage Display Methods for Detection of Bacterial Pathogens.- Molecular Imprinted Polymers for Biorecognition of Bioagents.- Microsystems.- Microfluidics-Based Lysis of Bacteria and Spores for Detection and Analysis.- Detection of Pathogens by On-Chip PCR.- Micro and Nanopatterning for Bacteria- and Virus-Based Biosensing Applications.- Microfabricated Flow Cytometers for Bacterial Detection.- Bacterial Concentration, Separation and Analysis by Dielectrophoresis.- Ultrasonic Microsystems for Bacterial Cell Manipulation.- Recent Advances in Real-time Mass Spectrometry Detection of Bacteria.