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Inhalt

Opening Remark.- Structural Correlates of Immune Microenvironment.- Session 1 Microenvironmental Aspects of Lymphatic Tissue.- Introduction: Microenvironments in the Lymphoid System.- Differentiation of B Lymphocytes from Stem Cell Precursors.- Hemopoietic Origin of B Cells in the Mouse.- Lymphocyte Differentiation in the Chicken Embryo - Relationship to the Microenvironment.- The Lymphoid Development of the Embryonic Chicken Thymus in Organ Culture.- Colonizing Capacity of Lymphoid Cells Injected into Syngeneic Hosts.- Differential Traffic Patterns of T and B Lymphocytes in Relation to Germinal Centre Development.- Ecotaxis of B Cells in the Mouse.- Homing of B-Lymphocytes to Follicles: Specific Retention of Immunologically Committed Cells.- Antigenic Markers on Lymphoid Cells Varying in Their Capacity to Recirculate.- Thymus Cell Migration: 3HTdR-Labeled and Theta-Positive Cells in Peripheral Lymphoid Tissues of Newborn Mice.- Lymph Node Function and Lymphocyte Circulation in the Pig.- Germinal Centers: A Microenvironment for the Production of Antibody Forming Precursors?.- Microenvironmental Aspects of Lymphatic Tissue: Summary.- Session 2 Interaction of Lymphatic Cells.- Introduction: Cell Cooperation in Antibody Production - A Perspective with Questions.- Functional Heterogeneity of Thymus-Derived Lymphocytes.- Some Cell Surface Properties of Thymus-Derived Lymphocytes in Bursectomized Chickens.- Studies on the Influence of T Cells in Antibody Responses of Mice to SIII and DNP-Lysine-SIII.- Induction of Anti-Hapten Antibody Responses against Haptens Conjugated to Autologous and Heterologous Proteins.- Contribution of B and T Lymphocytes to in vitro Chicken Proliferative Spleen Cell Reactions to Antigens.- Proliferation of Activated Thymocytes in Mixed Lymphocyte Reactions.- Lymphoid Cell Interactions in Cell-Mediated Immunity.- Appendix and Thymus Cell Synergism in the Direct and Indirect Plaque Forming Cell Response to Sheep Erythrocytes.- The Role of Soluble Factors in T-B Cell Collaboration.- Studies on the Source and Action of the T-Cell Replacing Factor (TRF).- Thymus Extracts Induce Differentiation of Thymus Derived Cells.- Interaction of Lymphatic Cells: Summary.- Session 3 Antigen Recognizing and Processing Cells.- Introduction: Antigen Recognizing and Processing Cells.- Immunoglobulin Surface Determinants on Chicken Lymphoid Cells.- Functional and Morphologic Characteristics of Complement Receptor Lymphocytes in Mice.- Stimulation of Mouse Thymocytes by Syngeneic Spleen Cells in Mixed Lymphocyte Reactions.- Differential Induction and Suppression of Direct and Indirect PFC Responses to TNP Conjugated to Heterologous Erythrocytes.- Reconstitution of Primary Response in vitro by Defined Peritoneal Cells.- Uptake and Degradation of a Synthetic Antigen by Mouse Macrophages Containing Different Levels of Lysosomal Enzymes.- Direct Evidence for Plaque Formation by Macrophages.- The Proportion of Lymphocytes Capable of Recognizing Strong Transplantation Antigens in vivo.- Recovery of the Immune Response after Depletion of Specific Cells.- Early Appearance of Antigen-Binding Cells to Two Different Antigens during Fetal Lymphoid Development.- Antigen Recognizing and Processing Cells: Summary.- Session 4 Cellular Aspects of Immune Deficiency Diseases.- Introduction: Cellular Aspects of Immune Deficiency Diseases Involving B Cells.- Enhancement of the Immune Response of Genetically Thymus-Less Mice by Different Cell Populations.- Thymus Factors and Immunity: Enhancement of Immunologic Maturation by a Purified Calf Thymus Extract.- Involution of the Thymus Dependent Lymphoid System.- A Study on Human T Lymphocytes, Their Function and Frequency in Some Diseases.- Evidence of Two Functionally Distinct Lymphocyte Populations in Man.- The Relation between Nutritional Deprivation and Immunity.- Combined System Immunodeficiency with DiGeorge Syndrome and Dissociation of PHA/MLC Responses.- Transplantation of Haemopoietic Stem Cell (HSC) Concentrates for Treatment of Immune Deficiency Disease.- Immunological and Clinical Effects of Transfer Factor in Anergic Subjects.- Cellular Aspects of Immune Deficiency Diseases: Summary.- Session 5 Lymphatic Tissue in Tolerance, Immunosuppression and Facilitation.- Introduction: Different Types of Immunological Unresponsiveness.- Mechanism of Antigen Binding to Receptor Antibody in B Cell Immunity and Tolerance in vitro.- Characteristics of B Cell Tolerance Induced with T-Independent Polysaccharides.- Cortisone Interfering with the Production of "T and B Cells".- Immunosuppression of the Thymectomized Fetal Lamb and Its Neonatal Reconstitution.- Antigen Recognition and Localization in RES Blockaded Mice: Morphologic and Immunologic Studies.- The Effect of Cyclophosphamide on the Primary Humoral Immune Response. The Immunological Priming.- Germinal Center in Rat Lymphatic Tissues after the Administration of L-Asparaginase.- Enhancement of Tumour Growth by Lymphoid Cells from Mice Treated with Antilymphocyte Globulin.- Role of the Spleen in Immunologic Enhancement of Kidney Grafts in Rats.- Tolerance in Ovum Fusion Derived Tetraparental Mouse in Chimaeras.- Role of IgG1 in Immunological Enhancement - Facilitation.- Lymphatic Tissue in Tolerance, Immunosuppression and Facilitation: Summary.- Session 6 Reaction of Lymphatic Tissue in Neoplastic Disease.- Introduction: Immune Reactions to Neoplastic Disease.- Foetal Liver Stem Cells Inhibition by Ehrlich Ascites Carcinoma.- Suppressed Plaque and Rosette-Formation by Spleen Cells of Mice Injected with Tumor Extracts.- Immunosuppressive Factors Associated with Tumors.- Effect of Therapy and Tumour Stage on Cellular Immunity to Bladder Carcinoma.- Phase Specific Surface Autoantigens on Membranes of Fetus and Tumors.- B Cell, T Cell and Monocyte Origin of the Guinea Pig L2C Leukemia, Mouse Lymphomas and Human Leukemias and Lymphoblastic Cell Lines.- Immunocytes and Leukemia Virus Infection: Effects on Bone Marrow and Thymus Cell Responses and Interactions.- Influence of the Lymphatic System on Development of a Virus-Induced Tumor (Reticuloendotheliosis) in the Chicken.- Immune Reactions of the Syngeneic Host after the Intradermal Injection of Tumor Cells and Microsomes.- Enhancement of Metastases by L-Asparaginase in Allogeneic and Isogeneic Mouse Tumor Systems.- Reaction of Lymphatic Tissue in Neoplastic Disease: Summary.- Session 7 Lymphatic Tissue in Immunopathology, with Special Reference to Delayed Hypersensitivity.- Introduction: Interaction between B and T Lymphocytes in Delayed Hypersensitivity.- Contact Sensitivity in the Pig.- The Effect of Lymphatic Interruption and Immediate Vascularization on the Afferent Arc of Skin Graft Rejection.- Homograft Sensitivity in the Mouse: The Periodic Redistribution of Sensitised Lymphoid Cells.- The Onset and Time-Course of Delayed-Type Hypersensitivity in Rats.- Adjuvants and in vitro Antibody Production.- Basophilic Leucocytes in Delayed-Type Hypersensitivity Reactions in Experimental Animals and Man.- Antibody and Cell Requirements for Cytotoxicity by Non-Immune Effector Cells.- The Induction of a Cellular Immune Reaction against Self-Antigens Present in the Thymus.- Germinal Center Formation in Response to Skin Grafted across Weak and Strong Histocompatibility (H2) Barriers.- Thymectomy and Bursectomy in Chickens with Simultaneous Experimental and Spontaneous Autoimmune Disease.- Possible Role of Lymphokines in the Development of Ectopic Lymphoid Foci in the Chicken.- Mediators of Cellular Hypersensitivity and Immunity Including Immunologically Specific Factors.- Lymphatic Tissue in Immunopathology, with Special Reference to Delayed Hypersensitivity: Summary.- Session 8 New Experimental Approaches.- Introduction: New Experimental Approaches.- Manipulation of Fertilised Mouse Eggs Applied to I…