From the "inventor of PET," this book is a comprehensive guide to PET and PET CT and serves as a valuable resource for practicing physicians and residents. The text covers topics ranging from the basic principles of physics, molecular assays, preparation of molecular imaging probes, and biochemistry relevant for PET. Additionally, clinical applications in cancer, cardiovascular diseases, and neurological disorders are thoroughly discussed. All of the contributors to this book are UCLA School of Medicine faculty members and have combined their areas of expertise to create the premier reference on PET. Each chapter provides a complete overview of the topic and guides the reader through the subject matter. Figures, tables, and solved example problems are integrated into the text.

Klappentext

This book is written as both a text and a reference book. It contains numerous images from the biological sciences and clinical practice, tables, graphs, and fig­ ures, as well as exercises that are worked out to aid the reader in understanding principles or solving problems. In some cases, derivations are placed in appen­ dices so as not to break up the flow of the subject matter in the text. The book is intended for a broad audience interested in molecular imaging with positron emission tomography (PET). It is expected that the readers will range from undergraduate, graduate, and medical students to residents, physi­ cians, and scientists with backgrounds from various physical, biological, and medical specialty areas. Each chapter presents material in a straightforward man­ ner that is well illustrated and explained. Because of the diverse audience for the book, certain chapters or sections of chapters will be of more interest than oth­ ers to certain segments of the readership. Chapter 1 introduces the fundamental physics upon which PET imaging sys­ tems is based and discusses in detail the technologies and methods used to pro­ duce PET images. The chapter starts out by reviewing the physics of positron emission and annihilation and explains how positron range and photon non­ colinearity in coincidence detection place certain limits on spatial resolution.

Inhalt

1 Pet: Physics, Instrumentation, And Scanners.- 2 Quantitative Assay Development for Pet.- 3 Electronic Generators.- 4 The Molecular Basis of Disease.- 5 Oncological Applications of Fdg-Pet.- 6 Positron Emission Tomography of The Heart: Methodology, Findings in the Normal and the Diseased Heart, and Clinical Applications.- 7 Molecular Imaging of Biological Processes with Pet: Evaluating Biologic Bases of Cerebral Function.