For the development of clinical decision support systems based on Bayesian networks, Mario A. Cypko investigates comprehensive expert models of multidisciplinary clinical treatment decisions and solves challenges in their modeling. The presented methods, models and tools are developed in close and intensive cooperation between knowledge engineers and clinicians. In the course of this study, laryngeal cancer serves as an exemplary treatment decision. The reader is guided through a development process and new opportunities for research and development are opened up: in modeling and validation of workflows, guided modeling, semi-automated modeling, advanced Bayesian networks, model-user interaction, inter-institutional modeling and quality management.

Dr.-Ing. Mario A. Cypko completed his PhD at the Computer Science department of the University of Leipzig, Germany. He was a postdoctoral research fellow in the Human Research Office of the European Space Agency in the Netherlands. He is currently a postdoctoral research assistant at the German Heart Center Berlin, Germany.

Autorentext
Dr.-Ing. Mario A. Cypko completed his PhD at the Computer Science department of the University of Leipzig, Germany. He was a postdoctoral research fellow in the Human Research Office of the European Space Agency in the Netherlands. He is currently a postdoctoral research assistant at the German Heart Center Berlin, Germany.

Inhalt
Patient-specific Bayesian Network in a Clinical Environment.- TreLynCa: A Tumor Board Decision Model for Laryngeal Cancer.- Model Validation and Tools for Guided BN Modeling.- GUI for PSBN-based decision verification.