Provides up-to-date information on the oncogenesis of AIDS-associated cancers and non-AIDS-defining malignancies more commonly observed in HIV-infected individuals

Describes the molecular biology of the causative viral agents

Documents the specific treatment required in the HIV/AIDS population

Klappentext
In this book, leading experts examine the clinical and biological aspects of viruses known to play a role in the oncogenesis of AIDS-associated cancers and non-AIDS-defining malignancies more commonly observed in HIV-infected individuals. Among the malignancies considered are those associated with Kaposi sarcoma-associated herpesvirus (KSHV) or EpsteinBarr virus (EBV), Merkel cell carcinoma due to Merkel cell polyomavirus (MCPyV), human papillomavirus (HPV)-associated anogenital and oropharyngeal cancers, and hepatitis B and C virus (HBV/HCV)-associated liver cancers. It also provides detailed information on the molecular biology of the causative viral agents and guidance on the specific treatment required in this special population. Covering all the important advances in our understanding made since the first edition was published in 2007, including the discovery and characterization of MCPyV, which brought the number of known human oncoviruses to seven, this new edition is a valuable resource for members of the scientific and healthcare community and active researchers in this field.

Zusammenfassung

AIDS is a major worldwide health care crisis. One of the most important aspects of the disease is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. Of particular note are viral-associated cancers.

Aids-Associated Viral Oncogenesis will specifically address viral-induced human cancers. Topics will cover the viral associated cancers observed in the AIDS population, specific treatment required in this special population, and molecular biology of the causative viral agents.

Inhalt
V40 and AIDS-Related Systemic Non-Hodgkin's Lymphoma.- HIVHBV and HIVHCV Coinfection and Liver Cancer Development.icht nur um scientific background, sondern auch um treatment.