This book explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI, genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function, and molecular-level fMRI. Comprehensive and intuitively structured, this book examines the physiological basis of fMRI, the basic principles of fMRI and its applications, and the latest advances of the technology. The final chapter discusses the field's future.

fMRI: From Nuclear Spins to Brain Function is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology, and MRI physics.

This book also:

· Explores a wide range of topics, covering the physical basics, physiological bases, a selection of various applications, and cutting-edge advances in fMRI

· Engages the reader with a first-person account of the development and history of the fMRI field by the authors

· Discusses fMRI applications in a variety of contexts, including fMRI of the visual system, auditory cortex, and sensorimotor system as well as the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, and quantitative fMRI

Inhalt

1 From BOLD CONTRAST to IMAGING HUMAN BRAIN FUNCTION.-2 The Birth of Functional MRI at the Medical College of Wisconsin.-3 The road to fMRI using endogenous MR blood contrast.-4 Neurovascular Coupling.-5 Locally Measured Neuronal Correlates of functional MRI Signals.-6 Anatomical basis for functional specialization.-7 Pulse sequences for fMRI.-8 fMRI mechanisms.-9 Quantitative fMRI.-10 Quality Assurance in Functional MRI .-11 Analysis of Functional MRI Data.-12 Functional MRI of the visual system.-13 Functional MRI of the auditory cortex.-14 fMRI of the Sensorimotor System.-15 Functional MRI: Approaches to Cognitive Neuroscience Applications.-16 Novel developments in cognitive fMRI .-17 Midbrain fMRI: Applications, limitations and challenges.-18 Clinical Applications of fMRI.-19 Animal Model Studies.-20 Information decoding from fMRI images.-21 Imaging Genetics with fMRI.-22 Combining fMRI with Other Modalities: Multimodal Neuroimaging.-23 High Resolution fMRI.-24 Field strength dependence of contrast and noise in fMRI.-25 Study of Brain Bioenergetics and Function using In Vivo MRS

-26 Contrast Agents for Molecular-Level fMRI

-27 The Future of Functional MRI.