Genetic investigations and manipulations of bacteria and bacteriophage have made vital contributions to our basic understanding of living cells and to the development of molecular biology and biotechnology. This volume is a survey of the genetics of bacteria and their viruses, and it provides students with a comprehensive introduction to this rapidly changing subject. The fifth edition has been extensively revised to reflect recent advances in the field. The book now has a reader-friendly look, with end-of-chapter questions, "Thinking Ahead" and "Applications" boxes to challenge students' comprehension and insights. A complete glossary of common terms has been revised and expanded.

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Fundamentals of Bacterial and Viral Genetics.- Replication and Analysis of DNA.- Mutations and Mutagenesis.- Transcription and Translation: Processes and Basic Regulation.- DNA Repair and Simple Recombination.- T4 Bacteriophage as a Model Genetic System.- Genetics of Other Intemperate bacteriophages.- Genetics of Temperate bacteriophages.- Transduction.- Genetic Transformation.- Conjugation and the Escherichia coli Paradigm.- Other Plasmids and Other Conjugation Systems.- Plasmid Molecular Biology.- Advanced Regulatory Topics.- Site-Specific Recombination.- Applied Bacterial Genetics.- Bacterial Evolution.- Glossary.- Appendix 1 Laws of Probability and Their Application to Prokaryote Cultures.- Appendix 2 Useful World Wide Web Sites for Bacterial Genetics.- Appendix 3.- Answers to Application Questions.- Index.