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Inhalt

Preface & Dedication; P.A. Quant, S. Eaton. Historical overview. Cambridge, colleagues, carnitine and ketogenesis .......; P.K. Tubbs. Carnitine and carnitine acyltransferases. 1. Biogenesis of the rat liver mitochondrial carnitine palmitoyltransferase I; I. Cohen, et al. 2. Subcellular distribution of mitochondrial carnitine palmitoyltransferase I in rat liver: Evidence for a distinctive N-terminal structure of the microsomal but not the peroxisomal enzyme; V.A. Zammit,et al. 3. Topology of hepatic mitochondrial carnitine palmitoyltransferase I; K. Kashfi, G.A. Cook. 4. Possible involvement of cytoskeletal components in the control of hepatic carnitine palmitoyltransferase I activity; G. Velasco, et al. 5. Regulation of beta-oxidation and CPT I activity by 3-thia fatty acids in cultured rat hepatocytes; J. Sleboda, J. Bremer. 6. Carnitine acyltransferases and associated transport systems in the endoplasmic reticulum; N.M. Broadway, et al. 7. Reciprocal enzymatic interference of carnitine palmitoyl transferase I and glycerol-3-phosphate acyltransferase in purified liver mitochondria; F. Beauseigneur, et al. 8. Control of human muscle carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor ; C. Mascaró, et al. 9. Kinetic investigation of carnitine palmitoyltransferases in homogenates of human skeletal muscle using L-aminocarnitine and malonyl-CoA; K. Hertel, et al. 10. Processing of carnitine octanoyltransferase pre-mRNAs by cis- and trans-splicing; C. Caudevilla, et al. 11. Selective modulation of carnitine long-chain acyltransferase activities: kinetics, inhibitors andactive sites of COT and CPT II; R.R. Ramsay, R.D. Gandour. 12. Confocal laser scanning microscopy of human skin fibroblasts showing transient expression of a green fluorescent carnitine palmitoyltransferase 1 fusion protein; F.R. van der Leij, et al. 13. Carnitine biosynthesis: purification of gamma-butyrobetaine from rat liver; F. Vaz, et al. Mitochondrial fatty acid oxidation and ketogenesis. 14. Hypolipidemic 3-thia fatty acids: Fatty acid oxidation and ketogenesis in rat liver under proliferation of mitochondria and peroxisomes; R.K. Berge, et al. 15. Molecular mechanisms of fatty acid &bgr;-oxidation enzyme catalysis; S.-Y. Yang, X.-Y. He. 16. Control of mitochondrial &bgr;-oxidation at the level of [NAD+]/[NADH] and CoA acylation; S. Eaton, et al. 17. Production and export of acyl-carnitine esters by neonatal rat hepatocytes; S. Eaton, et al. 18. Tissue specific differences in intramitochondrial control of &bgr;-oxidation; S. Eaton, K. Bartlett. 19. Endotoxin-induced changes in very-low-density lipoprotein and myocardial utilisation of triacylglycerol from abnormal VLDL in the rat; D.G. Hole, et al. 20. Effect of valproic acid on the expression of acyl-CoA dehydrogenases in various tissues; M. Nagao, et al. 21. Formation of a human `electron transferring flavoprotein': medium chain acyl CoA dehydrogenase complex - preliminary evidence from crosslinking studies; A. Parker, P.C. Engel. 22. Cloning and regulation of peroxisome proliferator-induced acyl-CoA thioestereases from mouse liver; M. Hunt, et al. 23. Metabolic effects of 3-thia fatty acids in cancer cells; K.J. Tronstad,