The Biogenesis of Cellular Organelles represents a comprehensive summary of recent advances in the study of the biogenesis and functional dynamics of the major organelles operating in the eukaryotic cell. This book begins by placing the study of organelle biogenesis in a historical perspective by describing past scientific strategies, theories, and findings and relating these foundations to current investigations. Reviews of protein and lipid mediators important for organelle biogenesis are then presented, and are followed by summaries focused on the endoplasmic reticulum, Golgi, lysosome, nucleus, mitochondria, and peroxisome.

Zusammenfassung

The Biogenesis of Cellular Organelles represents a comprehensive summary of recent advances in the study of the biogenesis and functional dynamics of the major organelles operating in the eukaryotic cell. This book begins by placing the study of organelle biogenesis in a historical perspective by describing past scientific strategies, theories, and findings and relating these foundations to current investigations. Reviews of protein and lipid mediators important for organelle biogenesis are then presented, and are followed by summaries focused on the endoplasmic reticulum, Golgi, lysosome, nucleus, mitochondria, and peroxisome.

Inhalt
Theory of Organelle Biogenesis.- Protein Coats As Mediators of Intracellular Sorting and Organelle Biogenesis.- The Role of Proteins and Lipids in Organelle Biogenesis in the Secretory Pathway.- Endoplasmic Reticulum Biogenesis.- The Golgi Apparatus.- Lysosome Biogenesis and Dynamics.- Nucleogenesis.- Mitochondrial Biogenesis.- The Biogenesis and Cell Biology of Peroxisomes in Human Health and Disease.