Cellular and Molecular Control of Neuronal Migration provides an up-to-date collection of reviews on the molecular and cellular principles of neuronal migration in the mammalian brain. Over the last decades a rich catalogue of signaling molecules controlling neuronal migration has been compiled, and within this book an international panel of experts provides up-to-date discussions of the state of knowledge how these distinct signaling pathways regulate various aspects of neuronal migration. This book introduces the reader to the latest discoveries and concepts of neuronal migration enabled through the application of most sophisticated methods and cutting edge experimental approaches. Cellular and Molecular Control of Neuronal Migration also provides an update on the underlying cellular and molecular basis of neurodevelopmental migration disorders in human patients for all interested neuroscientists and clinicians.

Klappentext

Cellular and Molecular Control of Neuronal Migration provides an up-to-date collection of reviews on the molecular and cellular principles of neuronal migration in the mammalian brain. Over the last decades a rich catalogue of signaling molecules controlling neuronal migration has been compiled, and within this book an international panel of experts provides up-to-date discussions of the state of knowledge how these distinct signaling pathways regulate various aspects of neuronal migration. This book introduces the reader to the latest discoveries and concepts of neuronal migration enabled through the application of most sophisticated methods and cutting edge experimental approaches.
Cellular and Molecular Control of Neuronal Migration also provides an update on the underlying cellular and molecular basis of neurodevelopmental migration disorders in human patients for all interested neuroscientists and clinicians.

Inhalt

Preface.- Molecular Pathways Controlling the Sequential Steps of Cortical Neuron Migration.- The Dynamics of Neuronal Migration.- The Impact of JNK on Neuronal Migration.- Novel Functions of Core Cell Cycle Regulators in Neuronal Migration.- Microtubules and Neurodevelopmental Disease: The Movers and the Makers.- Mark/Par-1 Marking the Polarity of Migrating Neurons.- The PAR Polarity Complex and Cerebellar Granule Neuron Migration.- Spinal Motor Neuron Migration and the Significance of Topographic Organization in the Nervous System.- Extracellular Signals Controlling Neuroblast Migration in the Postnatal Brain.