Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions.

This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature's longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the sixth volume of a continuing series.

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Sherri M. Biendarra-Tiegs, Frank J. Secreto, and Timothy J. Nelson, M.D., Ph.D. Addressing variability and heterogeneity of induced pluripotent stem cell-derived cardiomyocytes

Justine Bajohr, Maryam Faiz Direct Lineage Reprogramming in the CNS

Yusuke Nakamura, Yasuo Shimizu Induced pluripotent stem cells for regenerative medicine: Quality control based on evaluation of lipid composition

Omair A. Mohiuddin, Brett Campbell, J. Nicholas Poche, Caasy Thomas-Porch, Daniel A. Hayes, Bruce A. Bunnell, Jeffrey M. Gimble Decellularized Adipose Tissue: Biochemical composition, in vivo analysis and potential clinical applications

**Özge Sezin SOMUNCU **DECELLULARIZATION CONCEPT IN REGENERATIVE MEDICINE.

Janja Zupan , Matej Drobni , Klemen Straar Synovium-derived mesenchymal stem/ stromal cells and their promise for cartilage regeneration

Nur K****übra Ç****ankirili, Ozlem Altundag, Betül Çelebi-Saltik Skin stem cells, their niche and tissue engineering approach for skin regeneration

Fatima Aerts-Kaya, Baris Ulum, Aynura Mammadova, Sevil Köse, Gözde Aydn, Petek Korkusuz, Duygu Uçkan-Çetinkaya. Neurological regulation of the bone marrow niche

Rokas Miksiunas, Ali Mobasheri Daiva Bironaite Homeobox genes and homeodomain proteins: new insights into cardiac development, degeneration and regeneration

Victor Navarro-Tableros, Yonathan Gomez, Maria Felice Brizzi Giovanni Camussi ****Generation of human stem cell-derived pancreatic organoids (POs) for regenerative medicine