In the past, coronary arteriography was the only modality available to provide high quality images of the coronary anatomy. Quantitative coronary arteriography (QCA) was developed, implemented, validated and extensively applied to obtain accurate and reproducible data about coronary morphology and the functional significance of coronary obstructions. Over the last few years extensive basic technological research supported by clinical investigations has created competing modalities to visualize coronary morphology and the associated perfusion of the myocardial muscle. Currently, the following modalities are available: X-ray coronary arteriography, intracoronary ultrasound, contrast- and stress-echocardiography, angioscopy, nuclear cardiology, magnetic resonance imaging, and cine and spiral CT imaging. For all these imaging modalities, the application of dedicated quantitative analytical software packages enables the evaluation of the imaging studies in a more accurate, reliable, and reproducible manner. These extensions and achievements have resulted in improved diagnostics and subsequently in improved patient care. Particularly in patients with ischaemic heart disease, major progress has been made to detect coronary artery disease in an early phase of the disease process, to follow the atherosclerotic changes in the coronary arteries, to establish the functional and metabolic consequences of the luminal obstructions, and accurately to assess the results of interventional therapy. Aside from all these high-tech developments in cardiac imaging techniques, the transition from the analogue to the digital world has been going on for some time now. For the future, it has been predicted that the CD-R will be the exchange medium for cardiac images and DICOM-3 the standard file format. This has been a major achievement in the field of standardization activities. Since these developments will have a major impact on the way images will be stored, reviewed and exchanged in the near future, an important part of this book has been dedicated to DICOM and the filmless catheterization laboratory. Cardiovascular Imaging will assist cardiologists, radiologists, nuclear medicine physicians, image processing specialists, physicists, basic scientists, and fellows in training for these specialties to understand the most recent achievements in cardiac imaging techniques and their impact on cardiovascular medicine.

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Preface. Part One: Major Advances in Interventional Cardiology. 1. The Changing Role of High Speed Rotational Atherectomy in the Present and Future Practice of Coronary Intervention; S.H. Stertzer, et al. 2. The AVE Micro Stents®; S.H. Stertzer, E.V. Pomerantsev. 3. Non-Surgical Septum Reduction in Hypertrophic Cardiomyopathy; C. Knight, U. Sigwart. Part Two: Coronary Quantitation by QCA and Intracoronary Ultrasound (ICUS). 4. State of the Art in Quantitative Coronary Arteriography as of 1996; J.H.C. Reiber, et al. 5. 3-D Coronary Angiography for Quantitative Analysis of Coronary Morphology; H. Oswald, et al. 6. State of the Art in ICUS Quantitation; W. Li, et al. Part Three: Regression/Progression of CAD and Cardiovascular Imaging. 7. Imaging Atherosclerosis: Lesion vs. Lumen; M.V. McConnell, et al. 8. An Overview of Fluvastatin Clinical Trials; A. van Boven, P. Pfister. 9. Lessons Learned from Angiographic Coronary Atherosclerosis Trials; J.W. Jukema, et al. 10. Regression/Progression in Women: The Estrogen Angiographic Trials; D.M. Herrington. 11. Is Peripheral B-mode Ultrasound a Substitute for Coronary Arteriography? E. de Groot, et al. Part Four: DICOM and the Filmless Catheterization Laboratory. 12. The Digital Catheterization Laboratory - Is It Practical Today? J.T. Cusma, T.M. Bashore. 13. The Role of DICOM in the Digital Catheterization Laboratory; B. Goedhart, J.H.C. Reiber. 14. Philips CD-Medical - A New Era in Digital Cardiac Review,Exchange and Archiving; K. Vreeswijk. 15. Status of the GE Approach to the Digital Catheterization Laboratory; J.F. Nealon. 16. Requirements for Cardiac Interchange Media and the Adoption of Recordable CD; P.B. Condit, et al. 17. Status of the Camtronics Approach to the Digital Catheterization Laboratory; T.E. Kennedy, E.W. Bergholz. 18. The Approach at the German Heart Institute in Berlin &endash; the BERMED-System; E. Fleck, H. Oswald. 19. Archival Systems for Cineangiographic Film Replacement; D.R. Holmes, et al. Part Five: Progress in Intracoronary Ultrasound (ICUS). 20. What are the Advantages and Limitations of Three-Dimensional Intracoronary Ultrasound Imaging? E. Maurincomme, G. Finet. 21. New Developments in Intracoronary Ultrasound; C. Di Mario, et al. 22. Practical Integration of Intravascular Ultrasound Imaging into the Cardiac Catheterization Laboratory; G.S. Mintz, et al. 23. Intravascular Ultrasound for Evaluation of Coronary Arteries; G. Görge, et al. Part Six: Magnetic Resonance (MR) Coronary Imaging. 24. To Which Extent Can the Coronary Artery Tree be Imaged and Quantified With the Current MR Technology? A.C. van Rossum, J.C. Post. 25. Flow Measurements in Coronary Arteries Using MRI; M.A. Galjee. 26. Current and Future Applications of Magnetic Resonance Coronary Angiography; W.J. Manning. 27. Advantages and Limitations of Coronary MR Angiography. A.J. Duerinckx. Part Seven: Angioscopy. 28. Color Quantization in Angioscopic Images; J.A. Oomen, et al. 29. The