Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention

This book covers the molecular and cellular aspects of cancer metastasis, and discusses the clinical aspect of micro- and macro-metastases, which result in the death of the majority of patients with cancer. The current edition attempts to examine the current status of the basic scientific and clinical research in the area, and is a very useful reference for clinicians, oncologists, and biologists. It is intended for undergraduates as well as postgraduates in the area of medicine, oncology, and cancer biology.

Inhalt

Contributors. Metastatic Cascade, Molecular/Cellular Events and New Therapeutic Opportunities; W.G. Jiang, R.E. Mansel. The Role of Integrin-Mediated Processes in the Biology of Metastasis; J.F. Marshall, D. Davies. The Role of Hyaluronan and Its Degradation Products in Tumour Angiogenesis and Metastasis; D.C. West. The E-Cadherin/Catenin Complex in Invasion: The Role of Ectodomain Shedding; V. Noë, et al. Cancer and Cancer Metastasis-Related Genes; S. Hiscox. Hepatocyte Growth Factor and Met in Tumour Invasion-Metastasis: From Mechanisms to Cancer Prevention; K. Matsumoto, T. Nakamura. Tight Junctions, A Critical Structure in the Control of Cancer Invasion and Metastasis; W.G. Jiang, et al. Bone Marrow Micrometastases Detection and Significance; H. Singhal, M.P. Osborne. Polyunsaturated Fatty Acids and Their Role in Cancer Invasion and Metastasis; W.G. Jiang, et al. Metastatic Endocrine Cancer; G.P. Sadler, M.H. Wheeler. Prostate Cancer; M.D. Mason. Gastrointestinal Tumours: Cancer Metastasis, Molecular and Cellular Biology; L.J. Fon, P.D. Carey. Breast Cancer Metastasis; N. Khonji, et al. The Malignant Lymphomas; C.H. Poynton. Cancer Metastasis: Biological and Clinical Aspects, Gynaecological Cancer; M. Adams, B. Jasani. Index.