Cancer Diagnostics and Therapeutics

This book presents multiple facets of cancer biology, including cancer diagnosis, therapeutics to the latest developments in cancer informatics, and applications of artificial intelligence for improving oncologic care. The initial section of the book discusses factors contributing to the development and causes of cancer. The subsequent sections discuss the basic principle of imaging and therapeutic techniques, including MRI, CT, and positron emission tomography (PET) Scan. The book further, explores the implications of cancer chemotherapy on the immune system and emphasizes the effective management of cancer-related pain. Towards the end, it covers recent advancements in cancer treatment, including targeted therapy, immunotherapy, interventional radiotherapy, and stem cell-based therapy. Lastly, it summarizes essential strategic elements of cancer informatics for improving patient outcome.

Autorentext

Prof. (Dr.) S. K. Basu superannuated as a Professor from the Department of Computer Science, Banaras Hindu University, India. He served as Emeritus Professor in the School of Interdisciplinary Studies, S. N. Bose Innovation Centre, and Department of Computer Science and Engineering, Kalyani University, Kalyani, India. He obtained M.Sc degree in Physics, specializing in Biophysics. He achieved M.Tech degree from Indian Statistical Institute, Kolkata, India, and Ph.D degree from Jadavpur University, Kolkata, India. He had been a visiting scientist in different Indian institutes and abroad, and delivered lectures as a keynote and invited speaker. He had a teaching experience of more than 38 years and research experience of more than 32 years. During his career, he had supervised six Ph.D theses and two postdoctoral research works. His research interests were the diverse areas of Parallel and Distributed Processing, Simulation Modelling, Genetic Algorithms, Computer Systems, Wireless Sensor Networks, Biodiversity, Medical Expert Systems, Simulation and Modeling of Tumour Growth, etc. He had published more than 50 research articles in reputed international journals and conferences. He had authored and edited a number of books. He also published two books and edited/co-edited a number of books.

Dr. Chinmay Kumar Panda is a NASI Senior Scientist Platinum Jubilee Fellow, Department of Oncogene Regulation, Chittaranjan National Cancer Institute, Kolkata, India. He superannuated as a Senior Assistant Director Grade Scientist and Officer-in-Charge (Research) from the Chittaranjan National Cancer Institute in 2019. He received Ph.D degree in Biochemistry from the Calcutta University, India. His research interests include Molecular genetics of cancer, Regulation of gene expression, Development of molecular markers for early detection and prognosis of cancer, and Chemoprevention of cancer by natural products. He had done his post-doctoral training in Karolinska Institute, Stockholm, Sweden. He received different international fellowships like Swedish Institute fellowship, ICRETT fellowship of UICC. He is a fellow of The National Academy of Sciences, India (NASI) and West Bengal Academy of Science and Technology (WBAST).He is member of different scientific organizations like Society of Biological Chemists (India) (SBC(I)), Indian Association for Cancer Research (IACR), Indian Science Congress Association (ISCA) etc. He was President, New Biology Section of 106th ISCA Meeting in 2019. He is in the editorial board of different scientific journals like Scientific Reports, International Journal of Human Genetics. He has supervised a number of Ph.D, DNB and MD students for their thesis. He has over 200 publications in different peer reviewed journals, reviews and book chapters along with gene bank and GEO submissions.

Dr. Subrata Goswami, FIPP from the World Institute of Pain, USA, and Ph.D from Jadavpur University, India, is the Course Director at the ESI Institute of Pain Management, Kolkata, India since 2013. He is the Medical Officer in Charge at the Department of Pain and Palliative Medicine, ESI Hospital Sealdah, India since 2009. He is the Honorary Associate Editor of the Indian Journal of Pain, and the former National Vice President of the Indian Society for the Study of Pain (Indian Chapter of IASP) during 2017-2018. He is the life member of the International Association for the Study of Pain, World Pain Institute (USA), Indian Society of Anaesthesiologists, Indian Society for the Study of Pain, and Indian society of the Critical Care Medicine. He served as the Principal Investigator in two research projects funded by the National Jute Board, Government of India (2014-2017), and the Department of Science & Technology, Government of West Bengal, India (2018 - present), and as the co-investigators in other research projects. He authored more than 20 publications in journals of national/international repute, attended many national/international conferences and workshops, and also authored a number of chapters in pain management books.

Inhalt

Chapter 1 introductory cancer biology. -Chapter 2_Cancer: Getting informed about the Basics. -Chapter 3_Tumour Biology: An Introduction. -Chapter 4_Role of Angiogenesis in Tumour-Chapter 5_Biology, Chemistry and Physics of Cancer Cell Motility and Metastasis. -Chapter 6_MRI, CT, and PETSCAN: An Engineer's Perspective. -Chapter 7_Diffusion, MRI, and Cancer Diagnosis: Physicists' Outlook. -Chapter 8_Oncology: Radiation Oncologist's View. -Chapter 9_Radiomics: Comprehensive and Advance Image Analysis based Radiological Investigations. -Chapter 10_Oncology: Biochemists' Perspective. -Chapter 11_Oncology: Pathologist's View. -Chapter 12_Surgical Oncology: An Overview. -Chapter 13_Medical Oncology in Cancer Treatment. - Chapter 14_Effects of Cancer Chemotherapy on Immune System. -Chapter 15_Side-effects of Cancer Chemotherapy. -Chapter 16_Telomerase and its Therapeutic Implication in Cancer. -Chapter 17_Pain Management in Oncology. -Chapter 18_Other Approaches in Cancer Research: Stem-cell Research, Translational Research, and Immuno-therapy. -Chapter 19_Cancer Cell Lines: It's Implication in Therapeutics. -Chapter 20 Genomics of Cancer. -Chapter 21_Diabetes and Cancer Link. -Chapter 22_Cancer Genomics and Diagnostics: Northeast Indian Scenario. -Chapter 23_Oncology Informatics, AI and Drug Discovery. -Chapter 24_Statistics in Cancer: Diagnosis, Disease Progression, Treatment Efficacy and Patient Survival Studies. -Chapter 25_Epidemiology of Cancer: Asian Perspective.