Molecular Cardiology for the Cardiologist provides a short, easily readable summary of what the new biology brings to cardiology. With this in mind, special efforts have been made to present many comprehensive schemes and drawings, as well as teaching tables. The five parts of the book provide a general introduction to the new language of biology; the normal structure of the heart and blood vessels; the physiopathology and the new therapeutic avenues that have been opened up by the new biology. A concise summary of the keys that assist the cardiologist or student who seeks to learn and read more about this field. Provides practical examples to illustrate the clinical interest of the new approach.

Inhalt

Preface. 1: The new language of biology. From chromosome to gene. Current technologies. 2: Normal heart and vessels. Membrane proteins and electrical activity. Contractile proteins and contractility. Calciproteins and calcium movements. Collagen, ECM, and tissue compliance. Peptides regulating cardiac or vascular function. Cardiac and vascular growth. 3: Diseases of adaptation. Biological adaptation. The hypertrophied and failing heart. The senescent heart and vessels. 4: Genetics. DNA polymorphism. Inherited diseases. Inherited cardiovascular diseases and risk factors. 5: Gene transfers. Gene transfer during viral infection. Transgenic animals and reverse physiology. Gene therapy. References. Glossary. Index.