This book provides comprehensive coverage of the three most important themes in the field of Endocrine Disrupting Chemicals (EDC) research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs.

Zusammenfassung

Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians' office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.

Inhalt
The Basic Biology of Endocrine Disruption.- to Endocrine-Disrupting Chemicals.- Endocrine Disruption and the Female.- Endocrine Disruption in the Male.- Endocrine-Disrupting Chemicals and the Brain.- Heavy Metals as Endocrine-Disrupting Chemicals.- Cellular Mechanisms of Endocrine Disruption.- Endocrine Disruptors, Epigenetically Induced Changes, and Transgenerational Transmission of Characters and Epigenetic States.- The Biology of EDCs in Humans.- Implications of Thyroid Hormone Signaling Through the Phosphoinositide-3 Kinase for Xenobiotic Disruption of Human Health.- Endocrine Disruption and Reproductive Outcomes in Women.- Epidemiologic Evidence on the Relationship Between Environmental Endocrine Disruptors and Male Reproductive and Developmental Health.- Human Exposures and Body Burdens of Endocrine-Disrupting Chemicals.- Implications and Mitigations of EDCs.- Policy Implications of Endocrine-Disrupting Chemicals in Humans.- Talking With Patients and the Public About Endocrine-Disrupting Chemicals.- Community Interventions to Reduce Exposure to Chemicals with Endocrine-Disrupting Properties.- What Can We Do About Endocrine-Disrupting Chemicals?.