Stem cells and regenerative medicine have emerged as amongst the most exciting areas of biomedical and translational research, with huge anticipation for their use in restoration, repair and regeneration of human tissues and organs. Characterization of stem cells from various sources and attempts to demonstrate their potential in normal biological or pathological settings are two of the primary goals of the stem cell biologist. In this multidisciplinary volume, basic and clinical scientists cover both embryonic and adult stem cell sources, the current state of knowledge as well as the challenges that underlie translational medicine applications. Thus, the volume will be valuable for a broad audience of trainees (graduate students, post-doctoral fellows), and novice as well as more advanced researchers in the field of regenerative medicine.

Autorentext

Dr. Kursad Turksen is the Editor in Chief of the journal Stem Cell Reviews and Reports and the book series entitled Stem Cells and Regenerative Medicine that are published by Springer. He is also the editor of numerous protocol volumes published in Springer's Methods in Molecular Biology series.

Dr. Turksen is a Senor Scientist at the Ottawa Hospital Research Institute and his research interests cover the area of epidermal stem cells and the role of Claudins in the epidermal lineage.

Dr. Turksen is a Senor Scientist at the Ottawa Hospital Research Institute and his research interests cover the area of epidermal stem cells and the role of Claudins in the epidermal lineage.

Zusammenfassung
This volume will cover a series of reviews on stem cells including adult and embryonic stem cells. Speakers were invited to present these talks during the Stem Cell Symposia in fall of 2010, in Samsun, Turkey. Unique aspect of this volume is that it brings a multidisciplinary aspect of stem cells extracted from a symposium.

Inhalt

Introduction: Stem Cells in Samsun.- Searching for the in vivo Traces of MSCs and their Ancestors.- Isolation and Identification of Mesenchymal Stem Cells.- Mesenchymal Stromal Cells and Umbilical Cord Blood Transplantation.- Immunregulatory Functions of Mesenchymal Stromal Cells.- Mesenchymal Stem Cells: Possibilities of New Treatment Options.- Tissue Engineering Based on The Importance of Collaboration between Clinician and Basic Scientist and Mesenchymal Stromal Cells.- Synchroton Radiation and Nanotechnology for Stem Cell Researchers.- Controversies in Corneal Epithelial Stem Cell Biology.- Type 1 Diabetes and Stem Cells: A New Approach.- Successful Scaleup and Quality Assessments of Human Embryonic Stem Cells for Cell Therapy Challenges and Overview.- Human Embryonic Stem Cells from Laboratory and Clinical Perspective.- Clinical and Laboratory Aspects of Preimplantation Genetic Diagnosis and Derivation of Affected Human Embryonic Stem Cell Lines.- New Treatment Modalities by Disease and Patient Specific iPS Cells.- Cancer Stem Cells: Current Concepts and Therapeutic Implications.- Problems to be Solved in Molecular Oncology.