Asthma

The concept of asthma being an "allergic disorder only" has dominated above others to an extent, that a re-evaluation of this issue in the light of very recent results from research in immunopathology seemed more than overdue. This volume provides a current concept of theory and clinical practice of immunopathology and therapy of asthma, comprising extensive and brand new laboratory data on atopy, intrinsic asthma, aspects of autoimmunology, as well as guidelines for allergen avoidance, immunotherapy and - last not least - pharmacological treatment of cosinophilic inflammation.

The concept of asthma being an "allergic disorder only" has dominated above others to an extent, that a re-evaluation of this issue in the light of very recent results from research in immunopathology seemed more than overdue. This volume provides a current concept of theory and clinical practice of immunopathology and therapy of asthma, comprising extensive and brand new laboratory data on atopy, intrinsic asthma, aspects of autoimmunology, as well as guidelines for allergen avoidance, immunotherapy and - last not least - pharmacological treatment of cosinophilic inflammation.

Inhalt
/ Inhaltsverzeichnis.- T cells and other mononuclear cells in asthma / T-Zellen und andere mononukleäre Zellen beim Asthma.- IgE mediated antigen presentation / IgE-mediierte Antigenpräsentation.- The eosinophil and neutrophil granulocyte in asthma / Der eosinophile und neutrophile Granulozyt beim Asthma.- Cell biology and effector functions of the eosinophil leucocyte in bronchial asthma / Zellbiologie und Effektorfunktion des eosinophilen Leukozyten beim Bronchialasthma.- Immunological differences in allergic and intrinsic asthma / Immunologische Unterschiede zwischen allergischem und intrinsischem Asthma.- Similarities of exogenous and endogenous allergens; IgE-autoreactivity in atopic patients / Ähnlichkeiten zwischen exogenen und endogenen Allergenen: IgE-Autoreaktivität bei atopischen Patienten.- Oxidantien, bronchiale Hyperreagibilität und zelluläres Immunsystem / Oxidants, bronchial hyperreactivity and cellular immunity.- Schimmelpilzallergien und Asthma bronchiale / Differentiation of mould allergies in bronchial asthma.- Allergic asthma in children / Allergisches Asthma im Kindesalter.- Bronchial asthma. Definition and prognosis / Bronchialasthma: Definition und Prognose.- The future of immunotherapy / Die Zukunft der Immunotherapie.- Klinische Dokumentation des Erfolges einer Immuntherapie (IT) / Clinical documentation of success in immunotherapy of allergic asthma.- Bestimmung der Veränderungen allergenspezifischer IgE-, IgG- und IgG-Subklassenreaktivitäten in den Sera hyposensibilisierter Birkenpollen-allergischer Patienten mit Hilfe der Immunoblottechnik Korrelation mit Therapieerfolg? / Assessment of changes in allergen specific IgE, IgG and IgG-subclass reactivity in the serum of birchpollen-allergics under hyposensitisation, by means ofimmunoblottechniquescorrelation with clinical success?.- Allergenkarenz bei inhalativer Allergie / Avoidance of allergens in inhalative allergy.- Management of bronchial asthma. Summary of International Guidelines / Das Management der Asthmatherapie: Zusammenfassung internationaler Empfehlungen.- Richtlinien zur Diagnose und Therapie des Asthma Bronchiale.