Sodium Fluoride PET/CT in Clinical Use

This pocket book is the first of its kind on sodium fluoride (18F-NaF)-PET and addresses skeletal as well as cardiovascular applications. In malignant metastatic diseases 18F-NaF-PET has already demonstrated its benefits in cancer staging, re-staging, follow-up and response evaluation. It also has an emerging diagnostic role in the calcified soft-tissue metastases of primary bone tumours, and can be applied to evaluate cardiovascular diseases, such as calcifications in heart valves and peripheral vascular disease. The book is divided into 11 chapters: five on oncology, four addressing the general aspects of skeletal conditions, and two on cardiovascular diseases. It offers a valuable guide for referring colleagues, nuclear medicine physicians/radiologists and aid clinicians, and highlights the main applications and limitations of 18F-NaF-PET hybrid imaging (PET/CT).

Auteur

Prof. Kairemo graduated with an MSc (Eng) degree from Helsinki University of Technology in 1980 before undertaking medical training (MD, PhD) at the University of Helsinki, Finland. He subsequently completed specialist training in Clinical Chemistry, Nuclear Medicine and Clinical Pharmacology at Helsinki University Central Hospital (HUCH), followed by a research fellowship at Memorial Sloan-Kettering Cancer Center in New York (1989-93).
He has held posts as Professor of Clinical Chemistry at the Norwegian University of Science and Technology (1998-99), Professor of Nuclear Medicine at Uppsala University Hospital in Sweden (2001-05) and as Head of the Nuclear Medicine Division, Department of Oncology at HUCH (2004-09). From 2009 to 2018, he was Chief of Nuclear Medicine and Molecular Radiotherapy at the Docrates Cancer Center in Helsinki. Since 2015 he has also been a Visiting Professor (Nuclear Medicine) at the University of Texas MD Anderson Cancer Center.
Besides holding a few patents he has published more than 200 original articles in peer-reviewed journals. In 2012, he received the Lifetime Achievement Award from the World Association of Radiopharmaceutical and Molecular Therapy.

Dr. Homer A. Macapinlac is the James E. Anderson Distinguished Professor of Nuclear Medicine and Chair of the Department of Nuclear Medicine at the University of Texas M.D. Anderson Cancer Center in Houston, Texas. Dr. Macapinlac is certified by the American Board of Nuclear Medicine, with a Certificate of Added Qualification (CAQ) in Nuclear Cardiology. He was also elected as a fellow of the American College of Nuclear Physicians. Prior to coming to M. D. Anderson, he served as clinical director of the Laurent and Alberta Gershel Positron Emission Tomography Center of Memorial SloanKettering Cancer Center, New York.
Dr. Macapinlac is an active committee member of various groups, and has served as pastChair of the Institute of Clinical PET. He was Chair of the Society of Nuclear Medicine PET Center of Excellence and received the SNM Distinguished Service Award for this role. Dr. Macapinlac is also an expert consultant to the IAEA, and an International Visiting Professor for the Radiological Society of North America. He has 199 peer reviewed publications with 11,751 citations and h-Index of 57.

Contenu
Chapter 1 18F-Fluoride Imaging: Tracer and Technique Lesley Flynt and Richelle Millican

Chapter 2

18F-Fluoride Imaging: Normal variants and artefacts Xu Guofan

Chapter 3

Sodium fluoride imaging in oncology Kalevi Kairemo and Homer A. Macapinlac

Chapter 4

18F-Fluoride Imaging: Monitoring therapy Elba Etchebehere and Kalevi Kairemo

Chapter 5

Determination of Skeletal Tumor Burden on 18F-Fluoride PET/CT *Ana Emília Brito and Elba Etchebehere *

Chapter 6

18F-Fluoride: Benign Bone Disease Kalevi Kairemo and Homer A. Macapinlac

Chapter 7

Dynamic 18F-Fluoride Imaging Homer A. Macapinlac and Kalevi Kairemo

Chapter 8

18F-Fluoride Imaging: Atlas of interesting images (images with specific teaching points, tracer, technique and pitfalls) Xu Guofan

Chapter 9

Role of Sodium Fluoride-PET in Primary Bone Tumors Vivek Subbiah and Kalevi Kairemo

Chapter 10

18F-Sodium Fluoride Positron Emission Tomography in Cardiac Disease

Marwa Daghem and David E Newby

Chapter 11 18F-Sodium Fluoride positron emission tomography / computed tomography imaging of the peripheral vasculature Maaz BJ Syed, Jakub Kaczynski and David E Newby