Résumé
Frontmatter -- PREFACE -- Symposium Guests of Honour -- Symposium activities -- ON DAVID NACHMANSOHN'S RELATIONSHIP TO BERLIN -- CONTENTS -- David Nachmansohn (1899-1983): a pioneer of neurochemistry -- I. THE MOTOR ENDPLATE AND PRESYNAPTIC MECHANISMS -- REMODELLING OF NEUROMUSCULAR JUNCTIONS DURING REPAIR OF MUSCLE FIBRES -- INTERMITTENT, CALCIUM INDEPENDENT RELEASE OF ACETYLCHOLINE FROM MOTOR NERVE TERMINALS -- PROSTAGLANDINS MEDIATE THE MUSCARINIC INHIBITION OF ACETYLCHOLINE RELEASE FROM TORPEDO NERVE TERMINALS -- MOLECULAR MECHANISMS UNDERLYING ACETYLCHOLINE RELEASE -- ADENOSINE-5'-TRIPHOSPHATE AT THE CHOLINERGIC SYNAPSE: A CO-TRANSMITTER? -- SOLUBILIZATION, AFFINITY LABELLING AND PURIFICATION OF THE DIHYDROPYRIDINE RECEPTOR OF THE VOLTAGE-DEPENDENT CALCIUM CHANNEL FROM RABBIT SKELETAL MUSCLE TRANSVERSE TUBULE MEMBRANES -- IS ATP A GENERAL MOLECULAR CONSTITUENT OF CHOLINERGIC SYNAPTIC VESICLES? -- SINGLE CHANNEL FORMATION OF COOPERATIVELY INTERACTING UNITS OF THE HIGHLY-PURIFIED Na-CHANNEL PROTEIN -- K+-CHANNELS IN RAT VENTRICULAR CELLS SHOW VOLTAGE-DEPENDENT OUTWARD RECTIFICATION AND NON-LINEAR VOLTAGE TO CURRENT RELATION -- A PURIFICATION PROCEDURE OF THE TETRODOTOXIN BINDING COMPONENT CONTAINED IN THE ELECTROPLAXES OF ELECTROPHORUS ELECTRICUS -- HIGH-YIELD SYNTHESIS OF A NEW Na-CHANNEL MARKER : (3H)ETHYLENEDIAMINE DITETRODOTOXIN OR ED-diTTX -- INSECT OLFACTORY CELLS: ELECTROPHYSIOLOGICAL AND BIOCHEMICAL STUDIES -- EFFECTS OF EXTRACELLULAR ATP ON 86Rb INFLUX IN CHICK MYOTUBES; INDICATIONS OF A COTRANSMITTER ROLE IN NEUROMUSCULAR TRANSMISSION -- II. THE ACETYLCHOLINE RECEPTOR: STRUCTURAL ASPECTS -- A MONOCLONAL ANTIBODY SPECIFIC FOR ONE OF THE TWO AGONIST BINDING SITES AT THE ACETYLCHOLINE RECEPTOR -- THE MOLECULAR BIOLOGY OF ACETYLCHOLINE RECEPTORS -- ANTIBODIES TO SYNTHETIC PEPTIDES AS PROBES OF NICOTINIC ACETYL-CHOLINE RECEPTOR STRUCTURE -- REGULATION OF THE NICOTINIC ACETYLCHOLINE RECEPTOR BY PHOSPHORYLATION -- MOLECULAR INTERACTIONS BETWEEN THE MAJOR PROTEINS OF THE POSTSYNAPTIC DOMAIN IN TORPEDO MARMORATA ELECTROMOTOR SYNAPSE -- THE GLYCINE RECEPTOR OF RAT SPINAL CORD: PROGRESS IN THE INVESTIGATION OF A NEURONAL ION CHANNEL PROTEIN -- ANTIBODIES TO SYNTHETIC PEPTIDES AS PROBES FOR THE a-SUBUNIT AND FOR THE CHOLINERGIC BINDING SITE OF THE ACETYLCHOLINE RECEPTOR -- POSTSYNAPTIC MODULATION OF NEURONAL FIRING PATTERN BY ADENOSINE -- MAJOR PROTEINS OF THE ELECTRIC ORGAN FROM TORPEDO MARMORATA - POSSIBLE ASSOCIATIONS WITH THE POSTSYNAPTIC MEMBRANE -- PROTEIN-BLOT ANALYSIS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR -- III. THE ACETYLCHOLINE RECEPTOR: FUNCTIONAL ASPECTS -- ACETYLCHOLINE RECEPTOR (FROM ELECTROPIIORUS ELECTRICUS) : A COMPARISON OF SINGLE-CHANT JE], CUPREMT RECORDINGS A W CHE1TICAL KINETIC t'JEASURFMENTS -- PHOTOAFFINITY LABELING OF RECEPTOR STATES WITH MILLISECOND TIME RESOLUTION -- BINDING OF [3H] ACETYLCHOLINE TO ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA UNDER EQUILIBRIUM CONDITIONS: STOICHIOMETRY AND EVIDENCE FOR LONG-LIVED METASTABLE STATES -- THE DIMER OF TORPEDO ACETYLCHOLINE RECEPTOR: SYNCHRONIZED DOUBLE CHANNEL -- SYNCHRONIZATION OF ELECTRICALLY AND CHEMICALLY EXCITABLE ION CHANNELS -- EFFECTS OF HISTRIONICOTOXIN ON THE SYNAPTIC AND CONDUCTING MEMBRANES OF THE ELECTROPLAX -- THIAMINE TRIPHOSPHATE AS SPECIFIC OPERATING SUBSTANCE IN AXONAL CONDUCTION -- DOSE RESPONSE CURVES AT THE NEUROMUSCULAR JUNCTION -- NBD-5-ACYLCHOLINE IS A FLUORESCENT AGONIST OF THE MEMBRANE-BOUND ACETYLCHOLINE RECEPTOR FROM TORPEDO MARMORATA -- DO SIGMOID DOSE-RESPONSE CURVES REQUIRE THE ASSUMPTION OF ALLOSTERICITY? -- FOUNDATIONS OF THE ION FLUX METHOD -- SURFACE PROCESSES IN ION TRANSPORT AND EXCITATION -- CHEMICAL KINETIC INVESTIGATIONS OF THE EFFECTS OF CIS AND TRANS BIS-Q CN THE ACETYLCHOLINE RECEPTOR IN ELECTROPHORUS ELECTRICUS VESICLES -- DETERMINATION OF THIAMINE AND ITS PHOSPHATE ESTERS BY REVERSED-PHASE HPLC AT FEMTOMOLE LEVELS. APPLICATION TO BIOELECTROGENESIS -- IV. IMMUNOLOGY OF THE ACETYLCHOLINE RECEPTOR: MYASTHENIA GRAVIS AND SYNAPTIC PLASTICITY -- REGULATION OF THE IMMUNE RESPONSE TO THE ACETYLCHOLINE RECEPTOR AND OF EXPERIMENTAL MYASTHENIA -- CONGENITAL AND AUTOIMMUNE DISEASES OF THE NEUROMUSCULAR JUNCTION -- ANTI-IDIOTYPIC ANTIBODY TO THE ACETYLCHOLINE AND ADENOSINE RECEPTORS -- ANALYSIS OF THE PROPHYLACTIC AND THERAPEUTIC ACTION OF ELEC1RCLECHN IN EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS -- Regulation of Acetylcholine Receptors on Muscle in vitro by Central Nervous System Factors -- USE AND DISUSE AND THE CONTROL OF ACETYLCHOLINESTERASE ACTIVITY IN FAST AND SLOW TWITCH MUSCLE OF RAT -- THE EXPRESSION OF MICROTUBULE PROTEINS DURING THE DEVELOPMENT OF THE NERVOUS SYSTEM -- V. ACETYLCHOLINESTERASE AND CHOLINE ACETYLTRANSFERASE -- ACETYLCHOLINESTERASE OF MUSCLE AND NERVE -- EXPRESSION OF ACETYLCHOLINESTERASE IN MURINE NEURAL CELLS IN VIVO AND IN CULTURE -- THE INVOLVEMENT OF PHOSPHATIDYLINOSITOL IN THE ANCHORING OF HYDROPHOBIC FORMS OF ACETYLCHOLINESTERASE TO THE PLASMA MEMBRANE -- THE HY...