Population Genetics

Now updated for its second edition, Population
Genetics is the classic, accessible introduction to
the concepts of population
genetics. Combining traditional conceptual
approaches with classical hypotheses and debates, the book
equips students to understand a wide array of empirical
studies that are based on the first principles of
population genetics.

Featuring a highly accessible introduction to coalescent theory,
as well as covering the major conceptual advances in
population genetics of the last two decades, the second edition now
also includes end of chapter problem sets and revised coverage of
recombination in the coalescent model, metapopulation extinction
and recolonization, and the fixation index.

Auteur

MATTHEW B. HAMILTON, PHD, is Associate Professor of Biology at Georgetown University, where he teaches Population Genetics, Molecular Evolution, Evolutionary Processes, and similar undergraduate and graduate level courses. He is founding Director of Georgetown's Environmental Biology undergraduate major, past Director of the Georgetown Environment Initiative, and currently conducts research on the processes that influence the distribution of genetic variation within species.

Texte du rabat
A CONCISE INTRODUCTION TO THE CONCEPTS AND APPLICATIONS OF POPULATION GENETICS, FROM FIRST PRINCIPLES TO BASIC MODELING AND SIMULATION Population Genetics, Second Edition, provides an up-to-date introduction to the foundation of modern evolutionary biology: the study of the distribution of alleles in a population in relation to evolutionary processes and population structure. Designed for a full one-term course on population genetics, this accessible college-level textbook integrates foundational conceptual approaches, classical hypotheses, and traditional debates to help students understand a wide range of empirical studies based on the first principles of population genetics. In addition to gaining conceptual knowledge, students also develop algorithmic and computational skills that are central to prediction and data analysis in quantitative biology. This fully revised edition includes updates on topics such as effective population size, mutation rates and models, recombination in the coalescent model, measures and models of population differentiation, population assignment methods, and models of linked nucleotide site variation. New end-of-chapter problems include numerical and conceptual problems, applications using published data, and exercises that utilize simulation software. This popular textbook:

• Presents a comprehensive body of materials that support an innovative approach to teaching population genetics
• Describes the major conceptual advances in population genetics of the last two decades
• Is richly illustrated and includes numerous examples and case studies
• Offers a range of explanatory styles designed to engage different types of learners
• Features a highly accessible and thorough introduction to coalescent theory
• Provides step-by-step explanations of the mathematics required to understand the concepts covered in the text
• Includes boxes with in-depth mathematical derivations and reasoning
• Features Interact Boxes with exercises based on a rich set of spreadsheet models and web-based computer simulations built specifically for the text Population Genetics, Second Edition, is the perfect textbook for advanced undergraduate and graduate students in biology, genetics, ecology, evolutionary biology, agricultural genetics, molecular biology, and population-oriented medical genetics, and a valuable resource for other advanced students and practitioners wanting to expand their knowledge in population and evolutionary biology.

Résumé
Now updated for its second edition, Population Genetics is the classic, accessible introduction to the concepts of population genetics. Combining traditional conceptual approaches with classical hypotheses and debates, the book equips students to understand a wide array of empirical studies that are based on the first principles of population genetics.

Featuring a highly accessible introduction to coalescent theory, as well as covering the major conceptual advances in population genetics of the last two decades, the second edition now also includes end of chapter problem sets and revised coverage of recombination in the coalescent model, metapopulation extinction and recolonization, and the fixation index.

Contenu

Preface and acknowledgements

Chapter 1 Thinking like a Population Geneticist

Chapter 2 Genotype Frequencies

Chapter 3 Genetic Drift and Effective Population Size

Chapter 4 Population Structure and Gene Flow

Chapter 5 Mutation

Chapter 6 Fundamentals of Natural Selection

Chapter 7 Further Models of Natural Selection

Chapter 8 Molecular Evolution

Chapter 9 Quantitative trait variation and evolution

Chapter 10 The Mendelian basis of quantitative trait variation

Appendix

Literature cited

Index