Development of Plant-Based Medicines: Conservation, Efficacy and Safety

The `plant' is often the most neglected part of plant-based medicine. Throughout time, humans have searched, collected, and effectively used plants for healing. Currently, the medicinal plant-based business is flourishing at a dramatic pace and at the expense of an already declining population of plant species, many of which are on the verge of extinction. In spite of this history and popularity, the mystery of what transforms a plant into a medicinal plant persists, and there are chronic problems with ensuring the safety and efficacy of medicinal plant products. Therefore, there is a real need for a full characterization of medicinal plant species and for the development and application of novel technologies for the production of plant-based medicines.
This book highlights some of the recent advances and new approaches to the development of technologies for plant-based medicines and is intended to stimulate new discussions among researchers, regulatory authorities, and pharmaceutical organizations, leading to significant advancements in the field.

Contenu

Contributors. Acknowledgements. Preface. Conservation, Trade, Sustainability and Exploitation of Medicinal Plant Species; D.J. Leaman. An Overview of Recent Developments in Bioprospecting and Pharmaceutical Development; W. McClatchey, J. Stevens. Ancient-Modern Concordance in Ayurvedic Plants: Some Examples; S. Dev. Medicinal Plants of Egypt; M. El-Demerdash. Development of Plants in Central America; R.M. Romero. The Unique Challenges of Plant-Based Medicines; S.J. Murch, K.L. Choffe, P.K. Saxena. In Vitro Approaches to the Conservation and Development of Medicinal Plant Species; S.S.B. Campbell, S.J. Murch, P.K. Saxena. Large-Scale Production of Medicinal Plant Species: The Application of Bioreactors for Production of Ginseng Roots; S.H. Son, K.Y. Paek. Development of New Technologies for Medicinal Plant Species - Panax ginseng and Huperzia serrata: Cryopreservation and Analysis of Secondary Metabolites; W.L. Teng. Somatic Cell Fusion: Relevance to Medicinal Plants; S.J. Murch, P.K. Saxena. Plant-Derived Antibodies: The Medicines of Tomorrow; C. Sheedy, J.C. Hall. Latex Biochemistry of Certain Euphorbiaceous Taxa: Medicinal Importance; K. Seshagirirao, M.N.V. Prasad. Evaluation of Plant Extracts in Mammalian Systems: Applications of the Big Blue® Rodent Mutational Assay; J.G. de Boer. The Importance of Clinical Research for Plant-Derived Medicines; T. Gorski. Index.