Basic and Clinical Tumor Immunology

Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general onco­ logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often prelimi­ nary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by divid­ ing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Contenu

1. The immunological surveillance hypothesis.- 2. Role of macrophages in host resistance against tumors.- 3. Specific antitumor immunity and its role in host resistance to tumors.- 4. Cultured human antitumour T cells and their potential for therapy.- 5. Human tumor antigens: Detection and characterization with monoclonal antibodies.- 6. Immunocompetence in cancer patients.- 7. Biological response modifiers: Current status and prospects as anti-cancer agents.- 8. Therapy of established tumors by adoptive transfer of T lymphocytes.