Introduction to Basics of Pharmacology and Toxicology

This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics.

Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems.

This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Describes the pharmacology of drugs acting on different systems in the human body Analyses various human diseases and the pharmacological agents governing them Provides a valuable reference resource for academicians, researchers, and clinical practitioners

Auteur
Dr. Abialbon Paul completed his M.B.B.S. and M.D. in Pharmacology from Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER). He finished M.B.B.S. with distinction and four gold medals. Currently, he is working as an Assistant Professor of Pharmacology. During his post-graduation, he has been extremely passionate about teaching and research. The editor has been actively involved in the conduction of ethics committee meetings. He has published research articles and reviews in indexed journals and acted as a resource person/ faculty and organizing committee member of various academic programs including conferences, workshops and CMEs. He has been the Clinical Pharmacologist in-charge of the Madurai region of Apollo Hospitals where he had developed Antibiotic Stewardship programs and took charge of the medication management.

Dr. Nishanthi Anandabaskar has finished her M.B.B.S. and M.D. in Pharmacology from JIPMER, Puducherry. Currently, she is working as an Assistant Professor in the Dept. of Pharmacology, Sri Manakula Vinayagar Medical College and Hospital (SMVMCH), Puducherry, India. She was awarded the Prof. M.N. Ghosh gold medal (2017) for outstanding performance in Pharmacology. She has also completed the Postgraduate Diploma in Bioethics (PGDBE) from the PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India. She is a member of the Institutional Ethics Committee of SMVMCH, Puducherry and also of the Institutional Ethics Committee for observational studies in JIPMER, Puducherry, India. The editor has co-authored a book chapter on "Precision medicine in diabetes mellitus" in the book "Precision Medicine in Cancers and Non-Communicable Diseases" (CRC Press; ISBN: 9781315154749). She has also completed online certificate courses on Professional Diploma in Clinical Research (PDCR) and Advance Certificate Course in Scientific Writing from the Catalyst Clinical Services. Dr. Nishanthi has published research papers in Pharmacology in leading national and international biomedical journals.

Dr. Jayanthi Mathaiyan, M.B.B.S., M.D., D.N.B., is currently working as a faculty (Additional Professor and Head, Dept. of Pharmacology) at JIPMER involved in teaching, research and administrative activities. Dr. Jayanthi has a teaching experience of over a decade which includes taking lectures, question paper setting and evaluation of medical (M.B.B.S., M.D. Pharmacology), paramedical (B.Sc. Nursing, Medical Lab Technology and related courses) students, conducting orientation programmes to M.B.B.S., M.D. and Ph.D. students. Research activities include conducting & guiding M.B.B.S., M.D. and Ph.D. students for research in areas of interest. She has been involved in research in the fields of rational use of medicines, medication errors, pharmacogenomics and therapeutic drug monitoring for over 10 years. She has guided numerous projects involving research in the areas of medication errors with anticancer drug use, pharmacogenomics of diazepam, metformin and capecitabine. She has co-authored 30 indexed journal publications, both national and international and has also contributed chapters in medical books.

Dr. Gerard Marshall Raj holds an M.B.B.S. and M.D. in Pharmacology. Currently, he is working as an Assistant Professor in the Dept. of Pharmacology, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad Metropolitan Region, Telangana, India. He has contributed and co-edited the book 'Introduction to Basics of Pharmacology and Toxicology Volume 1: General and Molecular Pharmacology: Principles of Drug action' (Springer-Nature; ISBN: 9789813297784). He has also contributed book chapters in other books, namely, 'Intellectual Property Rights in Drug Development and Biotechnology' in the book 'Intellectual Property Issues in Biotechnology' (CABI; ISBN: 9781780646534), 'Intellectual Property Issues Surrounding Antimicrobial Agents' in the book 'Intellectual Property Issues in Microbiology' (Springer-Nature; ISBN: 9789811374654), and 'The Pharmacogenetics of Metformin' in the book 'The Pharmacological Guide to Metformin' (Nova Science Publishers; ISBN: 9781536166347). He was awarded the 'Prof. M. N. Ghosh Gold Medal' for outstanding performance during the M.D. Pharmacology course at JIPMER, Puducherry and has published many research articles, reviews, commentaries, case reports, and letters-to-the-editor in peer-reviewed and indexed journals.

Contenu
Part 1. Autonomic Nervous System.- Chapter 1. Cholinoceptor Agonists and Anticholinesterase Agents.- Chapter 2. Cholinoceptor Antagonists.- Chapter 3. Adrenergic Agonists.- Chapter 4. Adrenergic Antagonists.- Part 2. Central and Peripheral Nervous System.- Chapter 5. Neurotransmitters and Neurotransmission. Chapter 6. Hypnotics and Sedatives.- Chapter 7. Pharmacotherapy of Seizures.- Chapter 8. General Anesthetics.- Chapter 9. Drug Therapy of Psychosis and Mania.- Chapter 10. Pharmacotherapy of Depression and Anxiety DisordersChapter 11. Pharmacotherapy of Neurodegenerative Disorders.- Chapter 12. Opioid Agonists and Antagonists.- Chapter 13. Cognition enhancers, Psychostimulants and Psychedelic Drugs.- Chapter 14. Drug Dependence and Abuse.- Chapter 15. Local Anesthetics.- Chapter 16. Skeletal muscle relaxants. Part 3. Autacoids and Other Chemical Mediators.- Chapter 17. Histamine, Serotonin, Bradykinin, and the Ergot Alkaloids.- Chapter 18. Prostaglandins, Leukotrienes and Related Compounds.- Chapter 19. Non-Steroidal Anti-Inflammatory Medicines.- Chapter 20. Drugs Used in Rheumatoid Arthritis.- Chapter 21. Pharmacotherapy of Gout.- Chapter 22. Nitric oxide, Vasoactive Peptides and Purines.- Part 4. Cardiovascular and Renal Pharmacology.- Chapter 23. Drugs Affecting Renal Excretory Function.- Chapter 24. Antihypertensive Agents.- Chapter 25. Treatment of Ischemic Heart Disease.- Chapter 26. Drugs Used in Heart Failure.- Chapter 27. Drugs Used in Cardiac Arrhythmias.- Chapter 28. Pharmacotherapy of Shock and Drugs Used in Cardiopulmonary Resuscitation.- Chapter 29. Treatment of Pulmonary Arterial Hypertension.- Chapter 30. Antiplatelets, Anticoagulants and Fibrinolytics.- Chapter 31. Drugs Used in Dyslipidemias.- Part 5. Pulmonary Pharmacology.- Chapter 32. Treatment of Asthma and COPD.- Chapter 33. Drugs Used in Cough and Rhinitis.- Part 6 Gastrointestinal Pharmacology.-…