Autorentext

Gunther Winkelmann

Klappentext

Handbook of Microbial Iron Chelates emphasizes the various microbial compounds and synthetic analogues functioning as siderophores in microbes and as potential drugs in human iron metabolism. There are chapters describing the isolation, chemical characterization, synthesis and physicochemical properties of microbial iron chelates. Other chapters deal with the physiology and genetics of transport and receptors involved in iron uptake. Chemists, biologists, biochemists, pharmacologists, and medical doctors interested in the general aspects of iron metabolism, siderophores, receptors, and iron complex formation should consider this book a rich information source.

Inhalt
1.Detection, Determination, Isolation, Characterization and Regulation of Microbial Iron Chelates 2. Structures, Coordination Chemistry and Functions of Microbial Iron Chelates 3. Specificity of Iron Transport in Bacteria and Fungi. Genetics of Bacterial Iron Transport 4. Pyoverdins and Pseudobactins 5. Molecular Genetics of Siderophore Biosynthesis in Fluorescent Pseudomonads 6. Aqueous Solution Equilibrium and Kinetic Studies of Iron Siderophore and Model Siderophore Complexes 7. Isolation and Spectroscopic Identification of Fungal Siderophores 8. Synthesis of Catecholamide and Hydroxamate Siderophores 9. Biomimetic Siderophores 10. Therapeutically Useful Iron Chelates.