This book presents the papers that were delivered at the Satellite Symposium of the International Society for Neurochemistry in Padua, September, 1975. Having such Satellite Symposia was a new experiment for the Society, and all signs, including those from Padua, indicate that it was a very successful experiment, which will be an old tradition for the Society. The large international meeting affords the opportunity for presentations from all areas, for meeting of colleagues from various backgrounds and disciplines. The Satellite Symposia allow people from the same area of interest to discuss their subject in depth, and as such represent meetings of possibly the greatest practical significance for the partici pants. The Padua Symposium was no exception: all who particiDated in it could testify to its success in exchanging of information, learning of new approaches, and acqu~r~ng of new ideas, also the strengthening of old friendships, forming of new friendships and new collaborations, and exposing ideas to criticisms, suggestions, discussions. As a sign of the interest and success of the partici pants I can mention that all participants have sent in their contributions. Perhaps editors of volumes would anpreciate that the very last came in no later than two months past the deadline.

Inhalt
Section I Metabolite Transport.- Metabolite Transport at Cell Membranes.- Possible Role of Glutathione in Transport Processes.- Section II Barriers in the Living Brain.- Transport Mechanisms in the Cerebrospinal Fluid System for Removal of Acid Metabolites from Developing Brain.- The Morphological Approach to the Study of Normal and Abnormal Brain Permeability.- The Transport of Metabolizable Substances into the Living Brain.- The Specificity of Amino Acid and Sugar Carriers in the Capillaries of the Dog Brain Studied in Vivo by Rapid Indicator Dilution.- Possible Role of Insulin in the Transport of Tyrosine and Tryptophan from Blood to Brain.- The Influence of Liver-Bypass on Transport and Compartmentation in vivo.- Certain Aspects of Drug Distribution to Brain.- Penetration of Proteins in the Central Nervous System.- Section III Transport Studies in Various Nervous Tissue Preparations.- The Characteristics of Glucose Transport Across the Blood Brain Barrier and its Relation to Cerebral Glucose Metabolism.- Mechanisms for the Passive Regulation of Extracellular K+ in the Central Nervous System: The Implications of Invertebrate Studies.- Amino Acid Transport in Spinal and Sympathetic Ganglia.- Uptake of Neurotransmitters and Precursors by Clonal Cell Lines of Neural Origin.- On the Uptake Mechanism of Choline in Nerve Cell Cultures.- The Uptake and Release of ?-Aminobutyric Acid (Gaba) by the Retina.- Amino Acid Transport in Isolated Neurons and Glia.- Transport of Taurine in the Central Nervous System.- Transport of Adenine Derivatives in Tissues of the Brain.- Kinetical Analysis of the uptake of Glucose Analogs by rat Brain Cortex Slices from Normal and Ischemic Brain.- Uptake and Exchange of Gaba and Glutamate in Isolated Nerve Endings.- Mechanisms of Transport forthe Uptake and Release of Biogenic Amines in Nerve Endings.- Characteristics of the uptake and Release of Glutamic acid in Synaptosomes from rat Cerebral Cortex. Effects of Ouabain.- Release of Biogenic Amines from Isolated Nerve Endings.- Transport of Dopamine in Discrete Areas of the Striatum and of Cerebral Cortex in the Rat.- Section IV Factors Influencing Transport.- Energetics of Low Affinity Amino Acid Transport into Brain Slices.- Potassium Effects on Transport of Amino Acids, Inorganic Ions and Water: Ontogenetic and Quantitative Differences.- Evidence for a Synthesis-Dependent Release of Gaba.- Transport of Amino Acids and Catecholamines in Relation to Metabolism and Transmission.- Changes in Cerebral Amino Acid Transport During Development.- Section V Relationship of in vivo and in vitro Studies.- The Usefulness of Studies in vitro for Understanding Cerebral Metabolite Transport in vivo.- Release of Amino Acids from the Spinal Cord in vitro and in vivo.- The Distribution of Drugs in the Central Nervous System.- Section VI Alterations of Transport in Pathology.- Cerebral Permeability Phenomena in Epilepsy.- Pathological Aspects of Brain Transport Phenomena.- Brain Damage and Oral Intake of Certain Amino Acids.- Physiopathology of the Blood-Brain Barrier.- Brain Barrier Pathology in Acute Arterial Hypertension.- Author Index.