This timely volume explores tissue-derived stem cells, summarizing and evaluating the current body of knowledge. Sixteen chapters cover hematopoietic, osteoblast, skeletal, cardiac, pancreatic, epithelial, corneal, hepatic, renal, testicular, ovarian, fingernail, hair follicle and other stem cells- discussing their individual development, functions and pathologies, as well as the commonalities and interdependence between niches.

This installment of the popular Stem Cell Biology and Regenerative Medicine series delivers authoritative, international perspectives on this rapidly growing field. Tissue-Specific Stem Cell Niche is an ideal complementary volume to Biology of Stem Cell Niche and Adult Stem Cells, Second Edition and will be invaluable to clinicians and researchers working with stem cells as well as to postgraduate trainees who are studying them.

Thoroughly covers the topic; each chapter focuses on a specific tissue-specific stem cell niche Chapter authors present broad, international expertise and perspective Invaluable to clinicians, researchers, post doctorate and advanced graduate students and extremely useful as a complement to Biology of Stem Cell Niche and Adult Stem Cells, Second Edition Includes supplementary material: sn.pub/extras

Autorentext

Kursad Turksen received his Ph.D. from the University of Toronto in the area of osteoprogenitor biology and cell selection methodologies. He then did postdoctoral training at the Howard Hughes Medical Institute, University of Chicago, studying epidermal biology through use of genetically-altered mouse models. He joined the Ottawa Hospital Research Institute [previously known as the Loeb Research Institute] where he rose to the position of Senior Scientist in the Division of Regenerative Medicine. His research interests focus on stem cell biology, with a particular interest in the Claudin family of tight junction proteins and their role in epidermal lineage commitment and progression during development in health and disease. Dr. Turksen is currently Editor in Chief of the Springer journal Stem Cell Reviews and Reports in addition to serving as series editor for the Springer series Stem Cell Biology and Regenerative Medicine .

Inhalt
1 The hair follicle stem cell niche: the bulge and its environment.- 2 The sebaceous gland stem cell niche.- 3 Inner ear stem cell niche.- 4 Corneal Limbal Stem Cell Niche.- 5 Liver Stem Cell Niche.- 6 The elusive pancreatic stem cell.- 7 The Intestinal Stem Cell Niche.- 8 Dental Pulp Stem Cell Niche.- 9 **** Vascular Niche in HSC development, maintenance and regulation.- 10 Mesenchymal Stem Cell Niche of the Bone Marrow.- 11 Tendon stem cell niche.- 12 The Male Stem Cell Niche: insights from Drosophila and mammalian model systems.