This book focuses on the neural mechanisms and behavioral consequences of tinnitus. Coverage includes the neuroscience of tinnitus in animal models, from molecular mechanisms to cortical manifestation, as well as human brain responses and clinical management.

Tinnitus is a prevalent hearing disease, affecting 15% of the population, particularly hearing impaired, veterans and even young people who grow up with mp3 players and iPods. The mechanisms underlying tinnitus remain controversial. At present there is no cure for tinnitus, and treatment options are limited.

Different from previous tinnitus books, including A. R. Moller's book [in press at Springer], which typically have a strong clinical flavor, the present volume focuses on neural mechanisms of tinnitus and its behavioral consequences. The proposed book starts with a general summary of the field and a short introduction on the selection and content of the remaining chapters. Chapter 2 overviews tinnitus prevalence and etiologies to set the tone for significance and complexity of this neurological disorder spectrum. Chapters 3-8 cover neuroscience of tinnitus in animal models from molecular mechanisms to cortical manifestation. Chapters 9-12 cover human brain responses to tinnitus and it clinical management.

Focuses on neural mechanisms of tinnitus and its behavioral consequences Covers research and potential therapies in humans Discusses animal research that has led to increases in our understanding of the disease and its underlying mechanisms Includes supplementary material: sn.pub/extras

Klappentext
Tinnitus is a prevalent hearing disease in humans, affecting 15% of the population. At present there is no cure for tinnitus, and treatment options are limited. Recognizing the significance of tinnitus to hearing, as well as it serving as a window into the basic science of understanding of the hearing process, Tinnitus provides a broad overview of the topic. The volume focuses on neural mechanisms of tinnitus and its behavioral consequences. The book is divided into two parts to address systematically the current issues in tinnitus researchHistorical Reflections on Current Issues in Tinnitus- Jos J. Eggermont and Fan-Gang ZengBehavioral Tests for Tinnitus in Animals- Henry E. Heffner and Rickye S. HeffnerMolecular Mechanism of Tinnitus - Marlies Knipper, Marcus Müller, and Ulrike ZimmermannThe Cochlea and the Auditory Nerve as a Primary Source of Tinnitus- Régis Nouvian, Michel Eybalin, and Jean-Luc PuelDorsal Cochlear Nucleus: SomatosensoryAuditory Interactions in Tinnitus- Susanne Dehmel, Seth D. Koehler, and Susan E. Shore The Inferior Colliculus: Involvement in Hyperactivity and Tinnitus- Donald Robertson and Wilhelmina MuldersCortex: Way Station or Locus of the Tinnitus Percept?- Jos J. EggermontHuman Brain Imaging of Tinnitus - Jennifer R. MelcherThe Psychophysics of Tinnitus - Brian C. J. MooreStimulating the Auditory System to Treat Tinnitus: From Alleviatingthe Symptoms to Addressing the Causes - Arnaud J. Noreña Treatment: Pharmacological, Repetitive Transcranial Magnetic Stimulation, Epidural Stimulation, and Deep Brain Stimulation - Berthold Langguth, Dirk De Ridder, Tobias Kleinjung, and Ana Belén ElgoyhenAbout the Editors:Jos Eggermont is Professor in the Department of Physiology and Pharmacology, and the Department of Psychology at the University of Calgary, Alberta, Canada. Fan-Gang Zeng is Research Director in the Hearing and Speech Lab, University of California, Irvine. Arthur N. Popper is Professor in the Department of Biology and Co-Director of the Center for Comparative and Evolutionary Biology of Hearing at the University of Maryland, College Park. Richard R. Fay is Distinguished Research Professor of Psychology at Loyola University Chicago.About the Series: The Springer Handbook of Auditory Research presents a series of synthetic reviews of fundamental topics dealing with auditory systems. Each volume is independent and authoritative; taken as a set, this series is the definitive resource in the field

Inhalt
1.Historical Reflections on Current Issues in Tinnitus.- 2. Behavioral Tests for Tinnitus in Animals.- 3.Molecular Mechanism of Tinnitus.- 4.The Cochlea and the Auditory Nerve as a Primary Source of Tinnitus.- 5.Dorsal Cochlear Nucleus: SomatosensoryAuditory Interactions in Tinnitus.- 6.The Inferior Colliculus: Involvement in Hyperactivity and Tinnitus.- 7.Cortex: Way Station or Locus of the Tinnitus Percept?.- 8.Human Brain Imaging of Tinnitus.- 9. The Psychophysics of Tinnitus.- 10. Stimulating the Auditory System to Treat Tinnitus: From Alleviating the Symptoms to Addressing the Causes.- 11.Treatment: Pharmacological, Repetitive Transcranial Magnetic Stimulation, Epidural Stimulation, and Deep Brain Stimulation.