Update on arterial chemoreceptors Introduction to O2-sensing Comprehensive overview written by experts in the field

Klappentext

This book represents an updated review of the physiology of the carotid body chemoreceptors. It contains results in the topics at the frontiers of future developments in O2-sensing in chemoreceptor cells. Additionally, this volume provides data from studies carried out in other O2-sensing tissues including pulmonary vasculature and erythropoietin producing cells. It is a prime source of information and a guideline for arterial chemoreception researchers.

Inhalt
A TRIBUTE TO PROFESSOR AUTAR SINGH PAINTAL (1925-2004).- Immunolocalization of Tandem Pore Domain K+ Channels in the Rat Carotid Body.- Neuroglobin, a New Oxygen Binding Protein is Present in the Carotid Body and Increases after Chronic Intermittent Hypoxia.- Hypoxia-Inducible Factor (HIF)-1? and Endothelin-1 Expression in the Rat Carotid Body during Intermittent Hypoxia.- Expression of HIF-2? and HIF-3? in the Rat Carotid Body in Chronic Hypoxia.- Modulation of Gene Expression in Subfamilies of TASK K+ Channels by Chronic Hyperoxia Exposure in Rat Carotid Body.- Postnatal Changes in Gene Expression of Subfamilies of TASK K+ Channels in Rat Carotid Body.- Morphological Changes in the Rat Carotid Body in Acclimatization and Deacclimatization to Hypoxia.- Effect of Carbon Dioxide on the Structure of the Carotid Body A comparison between normoxic and hypoxic conditions.- S-Nitrosoglutathione (SNOG) Accumulates Hypoxia Inducible Factor-1? in Main Pulmonary Artery Endothelial Cells but not in Micro Pulmonary Vessel Endothelial Cells.- Changes in Antioxidant Protein SP-22 of Chipmunk Carotid Bodies during the Hibernation Season.- Potential Role of Mitochondria in Hypoxia Sensing by Adrenomedullary Chromaffin Cells.- Localization of Ca/Calmodulin-Dependent Protein Kinase I in the Carotid Body Chief Cells and the Ganglionic Small Intensely Fluorescent (SIF) Cells of Adult Rats.- Dual Origins of the Mouse Carotid Body Revealed by Targeted Disruption of Hoxa3 and Mash1.- Genetic Regulation of Chemoreceptor Development in DBA/2J and A/J Strains of Mice.- Genetic Influence on Carotid Body Structure in DBA/2J and A/J Strains of Mice.- The Effect of Hyperoxia on Reactive Oxygen Species (ROS) in Petrosal and Nodose Ganglion Neurons during Development (Using Organotypic Slices).-Carotid Body Volume in Three-Weeks-Old Rats Having an Episode of Neonatal Anoxia.- The Effect of Development on the Pattern of A1 and A2a-Adenosine Receptor Gene and Protein Expression in Rat Peripheral Arterial Chemoreceptors.- A Comparative Study of the Hypoxic Secretory Response between Neonatal Adrenal Medulla and Adult Carotid Body from the Rat.- In Search of the Acute Oxygen Sensor.- Does AMP-activated Protein Kinase Couple Inhibition of Mitochondrial Oxidative Phosphorylation by Hypoxia to Pulmonary Artery Constriction?.- Function of NADPH Oxidase and Signaling by Reactive Oxygen Species in Rat Carotid Body Type I Cells.- Hypoxemia and Attenuated Hypoxic Ventilatory Responses in Mice Lacking Heme Oxygenase-2.- Regulation of a TASK-like Potassium Channel in Rat Carotid Body Type I Cells by ATP.- Accumulation of Radiolabeled N-Oleoyl-Dopamine in the Rat Carotid Body.- Profiles for ATP and Adenosine Release at the Carotid Body in Response to O2 Concentrations.- Hypoxic Regulation of Ca2+ Signalling in Astrocytes and Endothelial Cells.- Does AMP-activated Protein Kinase Couple Hypoxic Inhibition of Oxidative Phosphorylation to Carotid Body Excitation?.- Mitochondrial ROS Production Initiates A?1-40-Mediated Up-Regulation of L-Type Ca2+ Channels during Chronic Hypoxia.- Acute Hypoxic Regulation of Recombinant THIK-1 Stably Expressed in HEK293 Cells.- Differential Expression of Oxygen Sensitivity in Voltage-Dependent K Channels in Inbred Strains of Mice.- An Overview on the Homeostasis of Ca2+ in Chemoreceptor Cells of the Rabbit and Rat Carotid Bodies.- Midbrain Neurotransmitters in Acute Hypoxic Ventilatory Response.- Chronic Intermittent Hypoxia Enhances Carotid Body Chemosensory Responses to Acute Hypoxia.- The Cell-Vessel Architecture Model for the CentralRespiratory Chemoreceptor.- Loop Gain of Respiratory Control upon Reduced Activity of Carbonic Anhydrase or Na+/H+ Exchange.- Adrenaline Increases Carotid Body CO2 Sensitivity: An in vivo Study.- Peripheral Chemoreceptor Activity on Exercise-Induced Hyperpnea in Human.- Effects of Low-Dose Methazolamide on the Control of Breathing in Cats.- Stimulus Interaction between Hypoxia and Hypercapnia in the Human Peripheral Chemoreceptors.- Gene Expression and Signaling Pathways by Extracellular Acidification.- Hypoxic Modulation of the Cholinergic System in the Cat Carotid Glomus Cell.- Are There CO2 Sensors in the Lung?.- Nitric Oxide in Brain Glucose Retention after Carotid Body Receptors Stimulation with Cyanide in Rats.- Pulmonary Nociceptors are Potentially Connected with Neuroepithelial Bodies.- Modulators of Cat Carotid Body Chemotransduction.- Identification and Characterization of Hypoxia Sensitive Kv? Subunits in Pulmonary Neuroepithelial Bodies.- Voltage-Dependent K Channels in Mouse Glomus Cells are Modulated by Acetylcholine.- Modification of the Glutathione Redox Environment and Chemoreceptor Cell Responses.- Carotid Body Transmitters Actions on Rabbit Petrosal Ganglion in Vitro.- Potassium Channels in the Central Control of Breathing.- Role of Endothelin-1 on the Enhanced Carotid Body Activity Induced by Chronic Intermittent Hypoxia.- Concluding Remarks.