This book will focus on the differentiation and regulation of subsets of CD4+ T cells. It will also cover other aspects of research on these cells, which has made great advances in recent years, such as subsets' plasticity and their role in healthy and disease conditions. The book provides researchers and graduate students with a cutting-edge and comprehensive overview of essential research on CD4+ T cells.

Summarizes cutting-edge research on CD4+ T cells differentiation Covers all major subsets of CD4+ T cells, as well as two untypical ones, Th9 and Th22 Suggests potential applications associated with CD4+ T cells in the clinic Includes supplementary material: sn.pub/extras

Autorentext
Dr. Bing Sun is a professor from Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS). He is the Chief Investigator of Lab of Molecular Immunology, Institute of Biochemistry and Cell Biology, CAS and Co-director of Institute Pasteur of Shanghai, CAS. His research focuses on immunity against viruses and Th1/Th2 cell regulation, and he has published more than 20 original research articles on top international peer-reviewed journals in this field.

Inhalt
Overview of orchestration of CD4+ T cell subsets in immune responses.- Th1/Th2 cell differentiation and molecular signals.- Th1/Th2 cell's function in immune system.- Regulatory T Cell differentiation and their function in immune regulation.- Th17 differentiation and their pro-inflammation function.- Tfh Cell differentiation and their function in promoting B cell responses.- Differentiation, Regulation and Function of Th9 Cell.- The biology and functions of Th22 cell