Still valid and useful after a decade, this work presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by world-renowned experts.

The invention of scanning tunneling microscopy (STM) in 1981 [1] and later atomicforcemicroscopy(AFM)in1986[2]facilitatedbreakthroughsinvarious disciplinesofsciencesuchaschemistry,physicsandbiology,andtrulyboosted the development of nanoscience and nanotechnology. These two techniques made it possible to achieve a detailed understa- ing of chemical and biological systems as well as phenomena across multiple lengthscales, and in particular downto thesub-nanometer scale. In fact STM and AFM are not simply microscopy tools, but they are also extremely useful techniques tochemistand biochemists. Forexample AFMandSTMoffers- theticchemiststhechancetoobservethemoleculestheyhavesynthesized,how theymoveand dance onasurface,howtheyrecognizeand communicate with each other, thus making it possible to cast new light onto the molecular int- actions[3]. Alongsidetheircapabilityofgeneratingartisticthree-dimensional pictures with nanoscale resolution, they also allowed the study of molecular based architectures beyond imaging, providing quantitative insight into va- ous physico-chemical properties [4] For instance, by manipulating molecules individually it is possible to bestow information onto their mechanical pr- erties andtoperformconstructionsonthenanoscale. In thelastfewyears the application of AFM and STM to study molecular systems in various envir- ments (e. g. , liquid, gas, vacuum) is paving the way towards the unraveling of complex characteristics and phenomena of nanostructured (bio)systems. Inthisvolumewehaveselected afewofthemostrelevantexamplesofAFM and STM based experiments on (bio)molecular based systems, which offer not only a close look into the nanoworld but also provide quantitative insight into various properties of molecular and polymeric systems, and ultimately highlight some technologicallyrelevant applications. I was delighted and felt privileged to work with an outstanding group of contributingauthors:Itrulythankthemforalltheirefforts. Iamalsograteful to Dr. Marion Hertel and Birgit Kollmar-Thoni for their invitation to edit this volume and for their assistance.

Presents critical reviews of the present position and future trends in modern chemical research Short and concise reports on chemistry, each written by the world renowned experts Still valid and useful after 5 or 10 years More information as well as the electronic version of the whole content available at: springerlink.com Includes supplementary material: sn.pub/extras

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ghlight some technologicallyrelevant applications. I was delighted and felt privileged to work with an outstanding group of contributingauthors:Itrulythankthemforalltheirefforts. Iamalsograteful to Dr. Marion Hertel and Birgit Kollmar-Thoni for their invitation to edit this volume and for their assistance.

Inhalt
Microcantilever Sensors.- Functionalization of Probe Tips and Supports for Single-Molecule Recognition Force Microscopy.- Molecular Workbench for Imaging and Manipulation of Single Macromolecules and Their Complexes with the Scanning Force Microscope.- Friction and Surface Dynamics of Polymers on the Nanoscale by AFM.- Exploring Electronic Transport in Molecular Junctions by Conducting Atomic Force Microscopy.- Two-Dimensional Nanotemplates as Surface Cues for the Controlled Assembly of Organic Molecules.- STM, STS and Bias-Dependent Imaging on Organic Monolayers at the SolidLiquid Interface.