Pediatric sleep-disordered breathing (SDB) has emerged as a prevalent problem in children. This unique, comprehensive and up-to-date review is the first full and critical review of the evidence on current therapeutic approaches to this clinical condition.

Sleep Disordered Breathing in Children: A Comprehensive Clinical Guide to Evaluation and Treatment is a comprehensive, timely and up-to-date review of pediatric sleep disordered breathing (SDB) and offers a thorough focus on several key areas: namely, the normal development and maturation of the airway and breathing during sleep, the techniques that are in place for assessment of SDB in children, the clinical manifestations and characteristics of several pediatric populations at risk for SDB, the implications of SDB in various end-organ systems, and, finally, a critical review of the evidence on current therapeutic approaches. This unique and complete text is of welcome interest to all practicing physicians and healthcare professionals who evaluate children with sleep problems -- namely pulmonologists, pediatricians, sleep physicians, pediatric neurologists, pediatric otolaryngologists, and family practitioners, as well as clinical researchers, pediatric nurse practitioners and respiratory therapists. Written by a distinguished and international panel of authors who are renowned experts in their field and who offer an expanded view of the problems associated with SDB, Sleep Disordered Breathing in Children: A Comprehensive Clinical Guide to Evaluation and Treatment is an indispensible resource for all physicians who evaluate children for sleep-disordered breathing.

Unique, comprehensive, up-to-date review of pediatric SDB issues First full critical review of the evidence on current therapeutic approaches to SDB Evaluation of all techniques in place for assessment of SDB in children Targeted overview of the clinical manifestations and characteristics of at-risk populations for SDB Chapters written by international, renowned group of authors

Inhalt

Part I. The Normal Upper Airway.- 1.Upper Airway Structure During Development.- 2.Functional Aspects and Upper Airway Control During Wakefulness and Sleep.- 3.Lymphadenoid Tissues in the Upper Airway.- 4.The Nasal Airway.- Part II. Sleep During Development.- 5.Neural Mechanisms of Sleep and Circadian Rhythms.- 6.EEG and Sleep During Development.- 7.Autonomic Cardiovascular Regulation during Sleep.- 8.Arousal: Ontology, Functional Anatomy, Methodology, and Consequences.- 9.Metabolic and Hormonal Regulation during Sleep.- 10.Chemoreceptors, Breathing, and Sleep.- 11.Pathophysiology of Pediatric Obstructive Sleep Apnea: Putting it All Together.- Part III. Diagnostic Assessment of Sleep and Breathing in Children.- 12.Clinical Evaluation of the Pediatric Patient.- 13.Actigraphy.- 14.Abbreviated/Portable Recordings.- 15.Overnight Sleep Study and MSLT.- 16.Upper Airway Imaging in Children with Obstructive Sleep Apnea Syndrome.- 17.The Omics Future: Genomics, Transcriptomics, and Proteomics.- 18.Pediatric Sleep Disordered Breathing: Criteria and Spectrum of Disease.- Part IV. SDB in Children.- 19.Apnea of Prematurity.- 20.Epidemiologic Aspects of Pediatric OSA around the World.- 21.Obesity and Sleep.- 22.Obstructive Sleep Apnea in Children with Down Syndrome.- 23.Children with Neuromuscular Disorders.- 24.Sleep Problems in Children with Sickle Cell Disease.- 25.Children with Craniofacial Syndromes.- 26.Epilepsy, Headache, and Sleep Disordered Breathing.- 27.Sleep and Breathing in Cystic Fibrosis.- 28.Asthma and Obstructive Sleep Apnea.- 29.Central Hypoventilation Syndromes.- 30.Healthcare Utilization and Pediatric Obstructive Sleep Apnea.- 31.Gastroesophageal Reflux and Sleep Disordered Breathing.- Part V. Consequences of SDB in Children.- 32.Behavioral Morbidity in Pediatric Sleep Disordered Breathing.- 33.Neurocognitive Function and Learning in Children with Sleep Disordered Breathing.- 34.Brain Regulatory Mechanisms Underlying Breathing: Insights forSleep Pathology.- 35.Cardiovascular Implications.- 36.Metabolic Consequences of Sleep Disorders.- 37.Enuresis and Obstructive Sleep Apnea in Children.- Part VI. Treatment of SDB.- 38.Adenotonsillectomy.- 39.Corticosteroids and Leukotriene Modifiers in Pediatric SDB.- 40.CPAP Treatment in Children.- 41.Mandibular Advancement Devices.- 42.Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS).