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RNA and DNA Diagnostics

  • Kartonierter Einband
  • 360 Seiten
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The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a sig... Weiterlesen
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Beschreibung

The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynman's famous statement "What I cannot create, I do not understand."


Inhalt
Electrochemical Biosensors for miRNA Detection.- Electrochemical Detection of RNA.- DNA and PNA probes for DNA Detection in Electroanalytical Systems.- DNA for Non-Nucleic Acid Sensing.- Aptamers in Oncotherapy.- Genotyping of Single Nucleotide Polymorphism.- Environmentally Responsive and Bright Fluorescent Probes Possessing Dansyl-modified Oligonucleotides under Hybridization of DNA and RNA.- Fluorescent Nucleic Acid Analogues in Research and Clinical Diagnostics.- Emergent Properties and Functions of Nanoconfined Nucleic Acid Architectures.- RNA and DNA Diagnostics on Microspheres: Current and Emerging Methods.- DNA and RNA Electronic Properties for Molecular Modifications and Environmental State Diagnostics.- Mechanochemical Sensing.- Microarrays as Research Tools and Diagnostic Devices.- Quadruplex Priming Amplification (QPA) for Nucleic Acid Diagnostics.- Single-molecule strategies for DNA and RNA diagnostics.- Detection and Assessment of microRNA Expression in Human Disease.

Produktinformationen

Titel: RNA and DNA Diagnostics
Editor:
EAN: 9783319361994
ISBN: 3319361996
Format: Kartonierter Einband
Herausgeber: Springer International Publishing
Genre: Medizin
Anzahl Seiten: 360
Gewicht: 546g
Größe: H235mm x B155mm x T19mm
Jahr: 2016
Auflage: Softcover reprint of the original 1st ed. 2015