Neurogenetic and Neurodevelopmental Disabilities

This book provides an extensive examination of the genetic and developmental factors that contribute to disabilities impacting the nervous system. This book explores the complex relationship among genetic factors, cerebral development, and neurological functionality, offering a comprehensive analysis of the way genetic mutations and developmental anomalies lead to a wide range of disabilities. The book is carefully structured through essential concepts, encompassing fundamental neurogenetics and chromosomal anomalies, as well as the clinical presentations related to the nervous system, motor functions, sensory organs, and multisystem engagement.

This book addresses the biological and clinical dimensions of neurogenetic and neurodevelopmental disabilities, thereby rendering it pertinent to researchers, clinicians, geneticists, neurologists, students, scholars and allied health professionals. The chapters are systematically arranged, begins with an introduction to neurogenetics and neurodevelopment thereafter comprehensive sections addressing genetic syndromes, the involvement of the immune and endocrine systems, disorders of the nervous system, and the broad systemic implications of neurological dysfunction. The book further elaborates the significance of early diagnosis, intervention, and the implementation of treatments to enhance patient outcomes.

The significance of this subject has increased markedly as a result of recent advancements in genetics, neurobiology, and diagnostic technologies, which are advancing the understanding and management of neurodevelopmental disabilities. Recent advancements in gene sequencing and molecular biology have discovered novel pathways and mechanisms underlying these conditions, thereby facilitating more precise diagnoses and personalized treatment strategies. This book offers complete explanation, rendering it essential for healthcare professionals, researchers, and students engaged in the domain of neurogenetic and neurodevelopmental disabilities.

Explores genetic, immune, and neurological bases of neurodevelopmental disabilities in depth Integrates clinical, biological, and multisystem perspectives for comprehensive understanding Bridges recent advances in genetics with practical approaches to diagnosis and intervention

Autorentext

Dr. Rishabha Malviya has completed B. Pharmacy from Uttar Pradesh Technical University and M. Pharmacy (Pharmaceutics) from Gautam Buddha Technical University, Lucknow Uttar Pradesh. His PhD (Pharmacy) work was in the area of Novel formulation development techniques. He has 14 years of research experience and has been working as Professor in the Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University since past 11 years. His area of interest includes formulation optimization, nanoformulation, targeted drug delivery, localized drug delivery and characterization of natural polymers as pharmaceutical excipients. He has authored more than 150 research/review papers for national/international journals of repute. He has 58 patents (19 grants, 38 published, 1 filed) and publications in reputed National and International journals with total of 300 cumulative impact factor. He has also received an Outstanding Reviewer award from Elsevier. He has authored/edited/editing 98 books (Wily, CRC Press/Taylor and Francis, Springer, River Publisher, IOP publishing and OMICS publication) and authored 165 book chapters. His name has been included in word’s top 2% scientist list for the year 2020, 2021, 2022, 2023, and 2024 by Elsevier BV and Stanford University. He is Reviewer/Editor/Editorial board member of more than 50 national and international journals of repute. He has invited as author for "Atlas of Science" and a pharma magazine dealing with industry (B2B) "Ingredient South Asia Magazines". Mr. Shivam Rajput has completed B. Pharmacy from Pt. B. D. Sharma University of Health Sciences, Rohtak, and M. Pharmacy from Galgotias University, Greater Noida. Currently he is working as assistant professor at Hindu College of Pharmacy, Sonipat, Haryana. His area of interest includes nano formulations, formulation optimization, cancer nanomedicine, targeted drug delivery system, pharmaceuticals and green nanotechnology. He has authored/edited/editing 16 books (Wily, CRC Press/Taylor and Francis, Springer, Bentham Publisher, and Jenny Stanford publication) and authored 45 book chapters. He has published good Scopus index papers with reputed publisher like Elsevier and Bentham Science. He has attended more than 10 international conferences.

Inhalt

Chapter 1: Introduction to Neurogenetic Disability.- Chapter 2: Genetic and Chromosomal Syndromes in Disability.- Chapter 3: Nervous System Disorders and Disability.- Chapter 4: Muscle and Motor System Disability.- Chapter 5: Sensory Organ Disorders and Associated Disabilities.