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For more than 30 years, the highly regarded Secrets Series® has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Rheumatology Secrets, 5th Edition, offers practical, up-to-date coverage of the full range of essential topics in this dynamic field. This highly regarded resource features the Secrets’ popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style-making inquiry, reference, and review quick, easy, and enjoyable.

• The proven Secrets Series® format gives you **the most return for your time-**succinct, easy to read, engaging, and highly effective
• Fully revised and updated throughout, offering practical coverage of basic immunology and pathophysiology, important disease manifestations, and clinical management issues related to common and uncommon rheumatic disorders, including a new chapter on IgG4-related disease
• Keeps you up to date with new techniques and technologies, as well as changing treatment options and drug information
• Helps ensure mastery of the material with more than 100 board-style questions available online that provide effective review and quick practice for your exams
• Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams
• An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

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SECTION I General Concepts

1. Top 100+ Rheumatology Secrets
2. Classification and Health Impact of the Rheumatic Diseases
3. Anatomy and Physiology of the Musculoskeletal System
4. An Overview of the Immune Response, Inflammation, and Autoimmunity

SECTION II Evaluation of the Patient With Rheumatic Symptoms
5. History and Physical Examination
6. Laboratory Evaluation
7. Arthrocentesis, Synovial Fluid Analysis, and Synovial Biopsy
8. Radiographic and Imaging Modalities
9. Electromyography and Nerve Conduction Studies
10. Approach for Patients With Monoarticular Arthritis Symptoms
11. Approach for Patients With Polyarticular Arthritis Symptoms
12. Approach to the Patient With Neuromuscular Symptoms
13. Perioperative Management of Patients With Rheumatic Diseases

SECTION III Systemic Connective Tissue Diseases
14. Rheumatoid Arthritis
15. Systemic Lupus Erythematosus
16. Drug-Induced Lupus Erythematosus
17. Systemic Sclerosis
18. Scleroderma Mimics
19. Idiopathic Inflammatory Myopathies
20. Mixed Connective Tissue Disease, Overlap Syndromes, and Undifferentiated Connective Tissue Disease
21. Sjögren Disease
22. Antiphospholipid Syndrome
23. Adult-Onset Still’s Disease
24. Polymyalgia Rheumatica

SECTION IV The Vasculitides and Related Disorders
25. Approach for Patients With Suspected Vasculitis
26. Large-Vessel Vasculitis: Giant Cell Arteritis, Takayasu Arteritis, and Aortitis
27. Polyarteritis Nodosa, Thromboangiitis Obliterans, and Primary Central Nervous System Vasculitis
28. Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
29. Immune Complex-Mediated Small-Vessel Vasculitides
30. Cryoglobulinemia
31. Behçet Syndrome
32. Relapsing Polychondritis

SECTION V Seronegative Spondyloarthropathies
33. Axial Spondyloarthritis
34. Rheumatic Manifestations of Gastrointestinal and Hepatobiliary Diseases
35. Reactive Arthritis
36. Arthritis Associated With Psoriasis and Other Skin Diseases

SECTION VI Arthritis Associated With Infectious Agents
37. Bacterial Septic Arthritis, Bursitis, and Osteomyelitis
38. Lyme Disease
39. Mycobacterial and Fungal Joint and Bone Diseases
40. Viral Arthritides
41. HIV-Associated Rheumatic Syndromes
42. Whipple Disease
43. Acute Rheumatic Fever and Poststreptococcal Arthritis

SECTION VII Rheumatic Disorders Associated With Metabolic, Endocrine, and Hematologic Diseases
44. Gout
45. Calcium Pyrophosphate Deposition Disease
46. Basic Calcium Phosphate and Other Crystalline Diseases
47. Endocrine-Associated Arthropathies
48. Arthropathies Associated With Hematologic Diseases
49. Malignancy-Associated Rheumatic Disorders

SECTION VIII Bone and Cartilage Disorders
50. Osteoarthritis
51. Metabolic Bone Disease
52. Paget Disease of Bone
53. Osteonecrosis

SECTION IX Hereditary, Congenital, and Inborn Errors of Metabolism Associated With Rheumatic Syndromes
54. Heritable Connective Tissue Diseases
55. Inborn Errors of Metabolism Affecting Connective Tissue
56. Storage and Deposition Diseases
57. Rheumatologic Manifestations of the Primary Immunodeficiency Syndromes
58. Skeletal Dysplasias

SECTION X Nonarticular and Regional Musculoskeletal Disorders
59. Approach for the Patient With Neck and Low Back Pain
60. Fibromyalgia
61. Regional Musculoskeletal Disorders
62. Sports Medicine and Occupational Injuries
63. Entrapment Neuropathies
64. Complex Regional Pain Syndrome

SECTION XI Neoplasms and Tumor-like Lesions
65. Benign and Malignant Tumors of Joints and Synovium
66. Common Bony Lesions: Radiographic Features

SECTION XII Pediatric Rheumatic Diseases
67. Approach to the Child With Joint Pain
68. Juvenile Idiopathic Arthritis
69. Juvenile Systemic Connective Tissue Diseases and Vasculitides
70. Kawasaki Disease

SECTION XIII Miscellaneous Rheumatic Disorders
71. Genetic Muscle Diseases: Metabolic and Other Genetic Muscle Disorders
72. Amyloidosis
73. Raynaud’s Phenomenon
74. Autoimmune Eye and Ear Disorders
75. Rheumatic Syndromes Associated With Sarcoidosis
76. IgG4-Related Disease
77. Rheumatic Disorders in Patients on Dialysis
78. Rheumatic Disease and the Pregnant Patient
79. Autoinflammatory Syndromes
80. Odds and Ends

SECTION XIV Management of the Rheumatic Diseases
81. Nonsteroidal Anti-Inflammatory Drugs
82. Glucocorticoids-Systemic and Injectable
83. DMARDs: csDMARDs and tsDMARDs
84. Disease Modifying Anti-Rheumatic Drugs: Biologic Agents
85. Immunosuppressive and Immunoregulatory Agents
86. Hypouricemic Agents and Colchicine
87. Bone Strengthening Agents
88. Rehabilitative Techniques
89. Surgical Treatment and Rheumatic Diseases
90. Disability

SECTION XV Final Secrets
91. Complementary and Alternative Medicine
92. History, the Arts, and Rheumatic Diseases