In this volume of Reviews of Physiology we present three articles on modulation of PKC in antitumor treatment, compartment-specific functions of the ubiquitin-proteasome pathway and transgenic models of alpha2-adrenergic receptor subtype function.

Inhalt
Modulation of protein kinase C in antitumor treatment.- Compartment-specific functions of the ubiquitin-proteasome pathway.- Transgenic models of ?2-adrenergic receptor subtype function.