Jetzt 20% Rabatt auf alle English Books. Jetzt in über 4 Millionen Büchern stöbern und profitieren!
Willkommen, schön sind Sie da!
Logo Ex Libris

Reviews of Physiology, Biochemistry and Pharmacology 147

  • Kartonierter Einband
  • 172 Seiten
(0) Erste Bewertung abgeben
Alle Bewertungen ansehen
Ligand-gated ion channels mediate fast synaptic transmission in the central nervous s- tem (CNS) and at ganglionic and neuromuscul... Weiterlesen
264.00 CHF 211.20
Sie sparen CHF 52.80
Print on Demand - Auslieferung erfolgt in der Regel innert 4 bis 6 Wochen.
Bestellung & Lieferung in eine Filiale möglich


Ligand-gated ion channels mediate fast synaptic transmission in the central nervous s- tem (CNS) and at ganglionic and neuromuscular synapses. The nicotinic acetylcholine - ceptor (nAChR) is a member of the ligand-gated ion channel superfamily, which includes the 5-HT , glycine and GABA type A and C receptors. These receptors are known as Cys- 3 loop receptors, as all of them have a conserved sequence containing a pair of cysteines separated by 13 residues and linked by a disulfide bridge. nAChRs can be divided into two groups: muscle receptors, which are found at the skeletal neuromuscular junction where they mediate neuromuscular transmission, and neuronal receptors, which are found throughout the peripheral and central nervous system. Many of the early studies carried out on the subunit composition and structure of the nAChRs were performed on receptors isolated from the electric organ of Torpedo californica, as this tissue is very rich in nAChRs, and they were found to have a high degree of homology with the embryonic v- tebrate muscle type receptor. Muscle nAChRs are made up of five subunits arranged around a central pore (Fig. 1A, B). In Torpedo electric organ and vertebrate fetal muscle, the subunit composition is (a1) b1gd, and in adult muscle the g subunit is replaced by the e to give an (a1)b1ed 2 2 composition (Mishina et al. 1986).

Nicotinic Acetylcholine Receptors: From Structure to Brain Function.- Cytochrome c Oxidase Structure, Function, and Physiology of a Redox-Driven Molecular Machine.- Peroxisome Biogenesis.- Outer Membrane Components of Type I Secretion Systems and Multidrug Efflux Pumps of Gram-Negative Bacteria


Titel: Reviews of Physiology, Biochemistry and Pharmacology 147
EAN: 9783642056833
ISBN: 3642056830
Format: Kartonierter Einband
Herausgeber: Springer Berlin Heidelberg
Anzahl Seiten: 172
Gewicht: 271g
Größe: H235mm x B155mm x T9mm
Jahr: 2010
Untertitel: Englisch
Auflage: Softcover reprint of hardcover 1st ed. 2003

Weitere Produkte aus der Reihe "Reviews of Physiology, Biochemistry and Pharmacology"