This book discusses both the beneficial and harmful aspects of NO in biology and medicine, and also introduces the emerging discovery of artemisinin in antitumor, antibacterial infection, anti-inflammation, and antiaging contexts. In 1992 nitric oxide (NO) was voted Molecule of the Year by Science magazine, and the discovery of its physiological roles has led to Nobel Prize-winning work in neuroscience, physiology and immunology. The book explains why we should maintain a steady-state NO level that is derived from neuronal or epithelial NO synthase, and avoid the extremely high NO level resulting from inducible NO synthase. The book offers a valuable resource for medical chemists, clinicians, biologists and all those interested in health and disease.

Introduces a uniform nitric oxide threshold theory in disease and health Explains why low-level nitric oxide is beneficial and high-level nitric oxide is harmful for health Guides people to understand the potential of artemisinin in antitumor, antibacterial infection, anti-inflammation, and antiaging Prospects to reveal the systemic and chronic low-grade inflammation as a common initiator of dermentia, obesity, and cancer Includes supplementary material: sn.pub/extras

Inhalt
Background.- Biological Features of NO and Pharmacological Principles of ART.- ART for Antitumor.- ART for Antibacterial Infection.- ART for Anti-inflammation.- ART for Antiaging.- Prospective.