This volume looks at classic and novel methods currently used by researchers to understand mood and anxiety disorders and foster precision medicine. Chapters in this book cover topics such as how the sucrose preference succeeds or fails as a measurement of anhedonia; fear conditioning in laboratory rodents; animal models for mania; rodent models for studying the impact of variation in early life mother-infant interactions on mood and anxiety; and prediction of susceptibility/resilience toward animal models of PTSD. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Comprehensive and cutting-edge, accommodating the novel views on how the neurobiology of psychiatric disorders should be reconceptualized, Psychiatric Vulnerability, Mood, and Anxiety Disorder s : Tests and Models in Mice and Rats is a valuable resource for all researchers interested in learning more about this important and developing field.

Includes cutting-edge methods and protocols Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts

Inhalt
Animal Models of Mood and Anxiety Disorders: The Pursuit of Standardization and Recognition of the Complex Neurobiology of Human Mental Health.- The Open Field Test.- The Light Dark Box Test in the Mouse.- The Olfactory Bulbectomized Rodent Remains a Valuable Preclinical Model of Depression and Antidepressant Activity.- Marble-Burying in Mice.- How the Sucrose Preference Succeeds or Fails as a Measurement of Anhedonia.- A Vogel Conflict Test Using Food Reinforcement in Mice.- Fear Conditioning in Laboratory Rodents.- Learned Helplessness in Rodents.- Chronobiology of Mood States: Introducing Circadian Animal Models.- Telemetry in Rats and Mice: Methodological Considerations and Example Studies of Stress and Anxiety in Ground-Based Spaceflight Analogs.- Utility and Implementation of Oral Corticosteroid Exposure in Behavioral Neuroscience Research with Rodents.- Animal Models for Mania.- Social Behavior Testing in Mice: Social Interest, Recognition, and Aggression.- Rodent Models for Studying the Impact of Variation in Early Life Mother-Infant Interactions on Mood and Anxiety.- Principles of Recording Rodent Ultrasonic Vocalizations.- Development of a Selectively Bred Mouse Model of Dominance and Submissiveness: Technical Considerations.- Prediction of Susceptibility/Resilience Toward Animal Models of Post-Traumatic Stress Disorder (PTSD).