This book presents an Assessment of Physical Sciences and Engineering Advances in Life Sciences and Oncology (APHELION) by a panel of experts. It covers the status and trends of applying physical sciences and engineering principles to oncology research in leading laboratories and organizations in Europe and Asia.

The book elaborates on the six topics identified by the panel that have the greatest potential to advance understanding and treatment of cancer, each covered by a chapter in the book. The study was sponsored by the National Cancer Institute (NCI) at the National Institute of Health (NIH), the National Science Foundation (NSF) and the National Institute of Biomedical Imaging and Bioengineering at the NIH in the US under a cooperative agreement with the World Technology Evaluation Center (WTEC).

Presents a cross-disciplinary overview of research at the interface of physical sciences and oncology Shows how concepts and models developed in biological physics can facilitate the understanding of tumor progression Informs scientists, engineers and policy makers of global trends in physical sciences and engineering in oncology Highlights opportunities for cooperation and collaboration for research groups and clinicians throughout the world Identifies major innovations and required investments at the physics/oncology interface for policy makers

Inhalt
Foreword.- Executive Summary.- Preface.- ToC.- List of Figures.-Chapter 1.- Introduction.- Chapter 2.- Complexity and Information: Cancer as a Multiscale Complex Adaptive System.- Chapter 3.- Mimicking the Microenvironement.- Chapter 4.- Cancer Cell Mechanics.- Chapter 5.- Fluid Mechanics and Transport in Tumors.- Chapter 6.- The Dynamics of Cell Motility.- Chapter 7.- Devices and New Diagnostic Principles.- Chapter 8.- Clinical Perspective.- Appendix A. APHELION Study Panelists and Advisors.- Appendix B. Site Visit Reports - Europe.- Appendix C. Site Visit Reports - Asia.- Appendix D. Site Visit Reports - United Kingdom.- Appendix E. Site Visit Reports - Brazil.- Appendix F. Recent Conferences.