This book gathers scientific contributions on comprehensive approaches to personalized medicine. In a systematic and clear manner, it provides extensive information on the methodological, technological, and clinical aspects of high-throughput analytics, nanotechnology approaches, microbiota/human interactions, in-vitro fertilization and preimplantation, and various diseases like cancer.Moreover, the book analyzes the social and legal aspects of social security systems, healthcare systems and EU law e.g. the role of solidarity, regulatory possibilities and obstacles, justice and equality, privacy/disclosure of data, and the right to know from an interdisciplinary perspective. Lastly, it explores the economical and ethical context in the fields of business models, intellectual property issues, the patient/physician relationship, and price discrimination.

Provides a new interdisciplinary approach to personalized medicine paradigms Includes chapters addressing medical, legal, and ethical issues Presents cutting-edge research findings

Inhalt

Part I.- Introduction.- Options for Realising and Financing Innovation in the German Healthcare System.- Clinical Evaluation of Medical Devices in Europe.- Personalized Medicine: Cutting Edge Developments.- Part II.- Methodological and Technological Aspects Important for Personalised Medicine.- Nanotechnology Approaches for Autologous Stem Cell Manipulation in Personalized Regenerative Medicine.- PatientDoctor Relationship: Data Protection in the Context of Personalised Medicine.- High-Throughput Analytics in the Function of Personalized Medicine.- BacteriaHuman Interactions: Leads for Personalized Medicine.- Present and Future in Personalized Clinical and Laboratory Approaches to In Vitro Fertilization Procedures..- Microbiota: Novel Gateway Towards Personalised Medicine.- The Right Not to Know in the Context of Genetic Testing.- Part III.- Social and Humanistic Aspects of Personal Medicine.- Personalized Medicine, Justice and Equality.- Evolution Paths of Business Models in Personalized Medicine.- Socio-Humanistic and Political Context of Personalized Medicine.- Personalized Medicine and Personalized Pricing: Degrees of Price Discrimination.- Personalised Medicine in Health Care Systems and EU Law: The Role of Solidarity?. Personalizing Privacy? Examining the Shifting Boundaries of a Fundamental Right in Preimplantation Genetic Testing of Embryos.- (Bio)ethical Aspects of Personalised Medicine: Revealing an Inconvenient Truth?.- Patient-Physician Relationship in Personalized Medicine.- Barriers Towards New Medicine: Personalized and Integrative Medicine Concepts.- The Reverse Payment Settlements in the European Pharmaceutical Market.- Doping in Sports: Legal and Other Aspects.- Personalised Medicine in Public Healthcare Systems.- Part IV.- Clinical Aspects of Personalised Medicine.- Targeted Breast Cancer Therapy.- Personalized Medicine in Ophthalmology: Treatment of Total Limbal Stem Cell Deficiency with Autologous Ex Vivo Cultivated Limbal Epithelial StemCell Graft.- Personalized Total Knee Arthroplasty: Better Fit for Better Function.- Comprehensive Approach to Personalized Medicine into Chronic Musculoskeletal Diseases.- Circadian Rhythms and Personalized Melanoma Therapy.- Genetic and Epigenetic Profiling in Personalized Medicine: Advances in Treatment of Acute Myeloid Leukemia.- The Future of Cartilage Repair.