This volume explores pericytes' roles under distinct pathological conditions, ranging from tumors, ALS, Alzheimer's disease, Multiple Sclerosis, stroke, diabetes, atherosclerosis, muscular dystrophies and more. Together with its companion volumes Pericyte Biology in Different Organs and Pericyte Biology Novel Concepts , Pericyte Biology in Disease presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cell biology and clinicians involved with these specific diseases.

Brings readers up to date on this unique cell type which has gone from almost forgotten to a timely, hot topic Updates on the most novel functions attributed to these cells All contributors are renowned international experts in the specialized field of pericytes in specific diseases

Autorentext

Alexander Birbrair received his Bachelor's Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette's laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).

Inhalt

Pericytes in cutaneous wound healing.- Pericytes in glioblastomas: multifaceted role within tumor microenvironments and potential for therapeutic interventions.- Pericytes in breast cancer.- Pericytes in sarcomas and other mesenchymal tumors.- Pericytes in metastasis.- The role of pericytes in Amyotrophic Lateral Sclerosis.- Pericytes in Alzheimer's Disease: novel clues to cerebral amyloid angiopathy pathogenesis.- Pericytes in Multiple Sclerosis.- Pericytes in ischemic stroke.- Pericytes in Hereditary Hemorrhagic Telangiectasia.- Pericytes in primary familial brain calcification.- Pericytes in type 2 diabetes.- Pericytes in atherosclerosis.- Pericytes in chronic lung disease.- Pericytes in muscular dystrophies.- Index . <p