The present book is an attempt to describe the most recent developments in the area of pericyte biology which is one of the emergent hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of thirteen detailed chapters on what we know so far about pericytes in distinct organs in physiological and pathological conditions. Further, it provides an update on the most novel functions attributed to these cells and will introduce a newer generation of researchers and scientists to the importance of these cells, ranging from their discovery in different organs through current state-of-the-science. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and vascular research.

This volume explores pericytes' physiologic roles in different tissues, ranging from the pancreas, lungs and liver through skeletal muscle, gut, retina and more. Together with its companion volumes Pericyte Biology in Disease and Pericyte Biology Novel Concepts, Pericyte Biology in Different Organs presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and researchers or clinicians involved with specific organs.

Brings readers up to date on this unique cell type which has gone from almost forgotten to a timely, hot topic Updates on the most novel functions attributed to these cells All contributors are renowned international experts in the specialized field of pericytes in specific organs

Autorentext

Alexander Birbrair received his Bachelor's Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette's laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC).

Klappentext

Inhalt

Pericytes in the retina.- Pancreatic pericytes in glucose homeostasis and diabetes.- Pericytes in the lung.- Pericytes in the skeletal muscle.- Pericytes in the gut.- Pericytes in the bone marrow .- Cochlear Capillary Pericytes.- Pericytes in the placenta: role in placental development and homeostasis.- Pericytes in the liver.- Pericytes in the Periodontal Ligament.- Pericytes in the heart.- Pericytes in the Umbilical Cord.- The pluripotent microvascular pericytes are the adult stem cells even in the testis.- Index . <p