The field of pediatric bone and soft tissue sarcomas has experienced a gradual but surprising transformation. Fundamental discoveries in the molecular biology of disease, recent breakthroughs in diagnostic imaging, and revolutionary surgical techniques have created unprecedented synergies and a refreshing vision with which to approach the diagnosis and treatment of these pediatric tumors. This book highlights the paths leading to the emergence of such a new vision and presents salient concepts in epidemiology, novel tools in imaging and molecular biology, and principles of drug development as the scaffold to understanding the pathophysiology and treatment of pediatric sarcomas. The book provides an up-to-date comprehensive reference text that articulates a multidisciplinary approach for the diagnosis and treatment of each of these often challenging diseases.

Integrates and summarizes clinical, molecular, and therapeutic aspects of pediatric bone and soft tissue sarcomas The authors are internationally renowned experts and scientists in their field Includes supplementary material: sn.pub/extras

Inhalt
Epidemiology of Bone and Soft Tissue Sarcomas.- Pathologic and Molecular Techniques Used in the Diagnosis and Treatment Planning of Sarcomas.- Diagnostic Imaging of Pediatric Bone and Soft Tissue Sarcomas.- Local Control Issues in Pediatric Bone and Soft Tissue Sarcomas.- Drug Discovery in Pediatric Bone and Soft Tissue Sarcomas Using In Vivo Models.- Pediatric Rhabdomyosarcoma: Biology and Results of the North American Intergroup Rhabdomyosarcoma Trials.- Non-Rhabdomyosarcoma Soft Tissue Sarcomas.- Fibrous and Fibrohistiocytic Tumors.- Ewing Sarcoma Family of Tumors.- Osteosarcoma.