This series does not include back cover copy.

The first time a connection has been made between Paraoxonases and inflammation, toxicology, and Infection in the same book Includes supplementary material: sn.pub/extras

Klappentext
This series does not include back cover copy.

Zusammenfassung
The pivotal role of the Paraoxonases (PON) family in a variety of inflammatory diseases; for eample, atherosclerosis, in preventing the toxicity of organophosphorus insecticides and nerve agents and a variety of other compounds has made them an interesting target for both clinicians and scientists alike.

Inhalt
ApoE Mimetic Peptide Reduces Plasma Lipid Hydroperoxide Content with a Concomitant Increase in HDL Paraoxonase Activity.- Interrelationships Between Paraoxonase-1 and Monocyte Chemoattractant Protein-1 in the Regulation of Hepatic Inflammation.- Biomarkers of Sensitivity and Exposure in Washington State Pesticide Handlers.- Paraoxonase 1 Status as a Risk Factor for Disease or Exposure.- Engineering Human PON1 in an E. coli Expression System.- The Toxicity of Mixtures of Specific Organophosphate Compounds is Modulated by Paraoxonase 1 Status.- Identification and Characterization of Biomarkers of Organophosphorus Exposures in Humans.- Temporal and Tissue-Specific Patterns of Pon3 Expression in Mouse: In situ Hybridization Analysis.- PON1 and Oxidative Stress in Human Sepsis and an Animal Model of Sepsis.- Paraoxonase 1 Attenuates Human Plaque Atherogenicity: Relevance to the Enzyme Lactonase Activity.- The Role of Paraoxonase 1 in the Detoxification of Homocysteine Thiolactone.- Alteration of PON1 Activity in Adult and Childhood Obesity and Its Relation to Adipokine Levels.- Anti-Inflammatory Properties of Paraoxonase-1 in Atherosclerosis.- Paraoxonase 1 Interactions with HDL, Antioxidants and Macrophages Regulate Atherogenesis A Protective Role for HDL Phospholipids.- The Effect of HDL Mimetic Peptide 4F on PON1.- The Contribution of High Density Lipoprotein Apolipoproteins and Derivatives to Serum Paraoxonase-1 Activity and Function.- Paraoxonase 1, Quorum Sensing, and P. aeruginosa Infection: A Novel Model.