Updated and expanded to reflect the growing literature on this widespread disorder, this second edition has a new editor and uses the same approach as the first, pairing a chapter on the basic science of a disorder followed by a one on its clinical aspects.

Completely revised and updated third edition, utilizing the most current evidence and practice guidelines for the treatment of osteoporosis

Discusses the basic aspects of bone metabolism, the pathophysiology of osteoporosis, current diagnostic techniques and medical treatment strategies

An excellent resource for endocrinologists, rheumatologists, orthopedic surgeons, primary and family care physicians and all specialties caring for patients with osteoporosis

Autorentext
Benjamin Z. Leder, MD, Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Marc N. Wein, MD, PhD, Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

Inhalt
Basic Aspects of Osteoblast Function.- Basic Aspects of Osteoclast Differentiation and Function.- Basic Aspects of Osteocyte Function.- Vitamin D and Bone Health: Basic and Clinical Aspects.- Basic Aspects of Bone Mineralization.- Determinants of Peak Bone Mass Acquisition.- Osteoporosis Screening and Diagnosis.- New Imaging Techniques for Bone.- Biochemical Markers of Bone Turnover.- Biomechanics of Bone.- Exercise in the Prevention of Osteoporosis-Related Fractures.- Effects of Estrogens and SERMs on Bone Metabolism: Clinical Aspects.- The Effects of Androgens on Bone Metabolism: Clinical Aspects.- Bisphosphonates: Mechanisms of Action and Role in Osteoporosis Therapy.- Denosumab: Mechanisms and Therapeutic Effects in the Treatment of Osteoporosis.- The Parathyroid Hormone Receptor Type 1.- PTH and PTHrP Analogs: Treatment of Osteoporosis.- Combination and Sequential Osteoanabolic/Antiresorptive Therapy in Osteoporosis Treatment.- Sclerostin Inhibition in the treatment of Osteoporosis.- Osteoporosis in Men. Glucocorticoid-Induced Osteoporosis.- Transplantation Osteoporosis.- Osteoporosis in Premenopausal Women.- Safety Considerations for Osteoporosis Therapies.- Genetic Determinants and Pharmacogenetics of Osteoporosis and Osteoporotic Fracture.